Evidence map›Paper›PMID 32857362›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2021

Apical Resection and Cryoinjury of Neonatal Mouse Heart.

Hua Shen, Ali Darehzereshki, Henry M Sucov, Ching-Ling Lien

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hua ShenDepartment of Stem Cell Biology and Regenerative Medicine, Broad CIRM Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Ali DarehzereshkiSaban Research Institute and Heart Institute, Children's Hospital Los Angeles, Los Angeles, CA, USA.
Henry M SucovDepartment of Stem Cell Biology and Regenerative Medicine, Broad CIRM Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Ching-Ling LienSaban Research Institute and Heart Institute, Children's Hospital Los Angeles, Los Angeles, CA, USA. clien@chla.usc.edu.

Funding

The complex genetics of heart regenerationR01HL144938 · NHLBI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI SUCOV, HENRY M · 2019 to 2025
$3.4M
NHLBI NIH HHS R01 HL144938
6 · The paper itself

Abstract

Neonatal mouse hearts have a regenerative capacity similar to adult zebrafish. Different cardiac injury models have been established to investigate the regenerative capacity of neonatal mouse hearts, including ventricular amputation, cryoinjury, and ligation of a major coronary artery. While the ventricular resection model can be utilized to study how tissue forms and regenerates de novo, cryoinjury and coronary artery ligation are methods that might better mimic myocardial infarction by creating tissue damage and necrosis as opposed to the removal of healthy tissue in the ventricular amputation model. Here we describe methods of creating ventricular resection and cardiac cryoinjury in newborn mice.

Indexed as

RegenerationVentricular RemodelingAnimalsAnimals, NewbornCardiac Surgical ProceduresCell ProliferationCryosurgeryFemaleHeartHeart InjuriesMaleMiceCardiomyocyte proliferationCryoinjuryNeonatal mouseScar formationVentricular apical resection

Identifiers

PMID32857362

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.