Evidence map›Paper›PMID 32857268›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2020

The association between self-reported health status and adverse events: a comparison among coronary artery bypass grafting (CABG) versus percutaneous coronary intervention (PCI).

Stine Nørris Nielsen, Trine Bernholdt Rasmussen, Jens Flensted Lassen, Selina Kikkenborg Berg, Lars Thrysoee, Jacob Eifer Møller, Lisette Okkels Jensen, Anne Langhoff Thuesen, Anne Vinggaard Christensen, Ola Ekholm and 3 more

Registry-linked trialOpen access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01926145 (DenHeart - Self-reported Health and Quality of Life at Hospital Discharge From a Heart Centre in Denmark), which is not on this map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01926145 completednot on this map

DenHeart - Self-reported Health and Quality of Life at Hospital Discharge From a Heart Centre in Denmark

TypeobservationalSponsorRigshospitalet, DenmarkRan2013 to 2014Enrolled16,712ConditionsAll Conditions Treated at the Heart Centres
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Stine Nørris NielsenDepartment of Cardiology, Odense University Hospital, J.B. Winsløws Vej 4, 5000, Odense C, Denmark. stine.noerris.nielsen@hotmail.dk.ORCID http://orcid.org/0000-0002-2858-7224
Trine Bernholdt RasmussenDepartment of Cardiology, Herlev and Gentofte University Hospital, Hellerup, Denmark.
Jens Flensted LassenDepartment of Cardiology, Odense University Hospital, J.B. Winsløws Vej 4, 5000, Odense C, Denmark.
Selina Kikkenborg BergDepartment of Cardiac, Vascular, Pulmonary and Infectious Diseases, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Lars ThrysoeeDepartment of Cardiology, Odense University Hospital, J.B. Winsløws Vej 4, 5000, Odense C, Denmark.
Jacob Eifer MøllerDepartment of Cardiology, Odense University Hospital, J.B. Winsløws Vej 4, 5000, Odense C, Denmark.
Lisette Okkels JensenDepartment of Cardiology, Odense University Hospital, J.B. Winsløws Vej 4, 5000, Odense C, Denmark.
Anne Langhoff ThuesenDepartment of Cardiac, Thoracic and Vascular Surgery, Odense University Hospital, Odense, Denmark.
Anne Vinggaard ChristensenDepartment of Cardiac, Vascular, Pulmonary and Infectious Diseases, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Ola EkholmNational Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.
Rikke MolsDepartment of Cardiology, Aarhus University Hospital, Skejby Sygehus, Aarhus, Denmark.
Charlotte Brun ThorupDepartment of Cardiology, Cardiothoracic Surgery and Clinical Nursing Research Unit, Aalborg University Hospital, Aalborg, Denmark.
Britt BorregaardDepartment of Cardiology, Odense University Hospital, J.B. Winsløws Vej 4, 5000, Odense C, Denmark.ORCID http://orcid.org/0000-0003-2702-0231
University of Southern Denmark · DKAalborg University Hospital · DKAarhus University Hospital · DKCopenhagen University Hospital · DKGentofte Hospital · DKOdense University Hospital · DKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWhile several studies have investigated clinical outcomes following coronary artery bypass grafting (CABG) vs. percutaneous coronary intervention (PCI), studies investigating self-reported health and the association with adverse outcomes are limited. Thus, the aim was to investigate differences in health-related quality of life (HRQoL), anxiety and depression at discharge and the association with a composite endpoint of the first event of acute cardiac readmission, revascularisation or 1-year mortality among patients undergoing CABG vs. PCI.

methodsData from the national cohort study, DenHeart, were used, including measures of HRQoL; EuroQoL-5D-5L (EQ-5D Index Score and VAS) and HeartQoL (Global, Physical and Emotional), anxiety and depression (Hospital Anxiety and Depression Scale, HADS) and register-based follow-up. A total of 7000 patients were included (CABG n = 652, PCI n = 6348) (median age 65, 75% men). Cox Proportional Hazard models were performed among a propensity-matched population of responders (n = 520).

resultsHRQoL was significantly better among patients undergoing PCI vs. CABG, but with no differences in time to readmission or revascularisation. HRQoL, anxiety and depression were significantly associated with the risk of the composite endpoint among the PCI group (Hazard Ratio, HR (95% confidence intervals, CI) [EQ-5D index score 3.07 (1.67-5.67), EQ-5D VAS 0.97 (0.96-0.99), HeartQol Global 0.61 (0.38-0.95), HeartQol Emotional 0.56 (0.39-0.80), HADS-D ≥ 8 3.12 (1.61-6.01), HADS-A ≥ 8 2.08 (1.14-3.80)].

conclusionPatients undergoing PCI reported better HRQoL at discharge compared with patients undergoing CABG, whereas readmission rates were similar. Self-reported health was associated with the risk of adverse events among patients undergoing PCI, but not among patients undergoing CABG. CLINICAL

trial registrationNCT01926145.

Indexed as

Health StatusAgedCohort StudiesCoronary Artery BypassDrug-Related Side Effects and Adverse ReactionsFemaleHumansMalePercutaneous Coronary InterventionQuality of LifeSelf ReportTreatment OutcomeAnxietyCardiac readmissionCoronary artery bypass graftingDepressionPercutaneous coronary interventionQuality of life

Identifiers

PMID32857268
OpenAlexW3082366921

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.