Evidence map›Paper›PMID 32857263›Full record

Observational studyJournal of neurology2021

Brainstem encephalitis in neuroborreliosis: typical clinical course and distinct MRI findings.

Thomas Pfefferkorn, Joachim Röther, Bernd Eckert, Hendrik Janssen

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Journal of neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Lyme neuroborreliosis as a cause of acute ischemic stroke: A case report.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Thomas PfefferkornDepartment of Neurology, Klinikum Ingolstadt, Krumenauerstrasse 25, 85049, Ingolstadt, Germany. thomas.pfefferkorn@klinikum-ingolstadt.de.ORCID http://orcid.org/0000-0002-7072-0295
Joachim RötherDepartment of Neurology, Asklepios Klinik Altona, Hamburg, Germany.
Bernd EckertInstitute of Radiology and Neuroradiology, Asklepios Klinik Altona, Hamburg, Germany.
Hendrik JanssenInstitute of Radiology and Neuroradiology, Klinikum Ingolstadt, Ingolstadt, Germany.
Asklepios Klinik Altona · DEKlinikum Ingolstadt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn this retrospective observational study and referring to a historical case presented in 2009, we searched for typical clinical and imaging features of brainstem encephalitis in neuroborreliosis.

methodsIn addition to the historical case we describe five affected patients.

resultsAll patients had a very similar prolonged clinical course with unspecific symptoms such as wasting, fatigue and headache. Brainstem signs were irregularly observed. MRI showed symmetrical brainstem alterations in all patients. In coronary FLAIR imaging these changes formed a figure resembling a Philippine tarsier.

conclusionsA subset of patients with neuroborreliosis develops a brainstem encephalitis with a typical clinical course and distinct MRI findings.

Indexed as

EncephalitisNervous System DiseasesBrain StemHeadacheHumansMagnetic Resonance ImagingBorreliosisEncephalitisMRI

Identifiers

PMID32857263
OpenAlexW3081713380

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.