Evidence map›Paper›PMID 32857243›Full record

ReviewCurrent diabetes reports2020

The Contribution of Kidney Disease to Cognitive Impairment in Patients with Type 2 Diabetes.

Shivani Ghoshal, Nicholette D Allred, Barry I Freedman

Open access · greenAbstract readReview
In one paragraph

Review in Current diabetes reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Diabetes, Albuminuria and the Kidney-Brain Axis.Journal of clinical medicine · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Shivani GhoshalDepartment of Neurology, Wake Forest School of Medicine, 1 Medical Center Blvd, Winston-Salem, NC, 27157, USA. sghoshal@wakehealth.edu.
Nicholette D AllredDepartment of Biochemistry and Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Barry I FreedmanDepartment of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, 1 Medical Center Blvd, Winston-Salem, NC, 27157-1053, USA. bfreedma@wakehealth.edu.
Wake Forest University · US

Funding

Metabolomics of Neurocognitive Risk for Dementia in DiabetesR01AG058921 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ALLRED, NICHOLETTE D. · 2019 to 2023
$3.8M
Cerebrovascular Disease and Cognitive Performance in African AmericansR01NS075107 · NINDS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI DIVERS, JASMIN, FREEDMAN, BARRY IRA · 2011 to 2015
$2.8M
NIA NIH HHS R01 AG058921NINDS NIH HHS R01 NS075107
6 · The paper itself

Abstract

purpose of reviewThis review focuses on the relationships between diabetes, cognitive impairment, and the contribution of kidney disease. RECENT

findingsWe review the independent contributions of parameters of kidney disease, including albuminuria, glomerular filtration, bone/mineral metabolism, and vitamin D synthesis, on cognitive performance in patients with diabetes. Potential pathophysiologic mechanisms underlying these associations are discussed highlighting gaps in existing knowledge. Finally, effects of the dialysis procedure on the brain and cognitive performance are considered. Emphasis is placed on novel non-invasive screening tools with the potential to preserve cerebral perfusion during hemodialysis and limit cognitive decline in patients with diabetic ESKD. Patients with type 2 diabetes and advanced chronic kidney disease suffer a higher prevalence of cognitive impairment. This is particularly true in patients with diabetes and end-stage kidney disease (ESKD).

Indexed as

Cognitive DysfunctionDiabetes Mellitus, Type 2Diabetic NephropathiesKidney Failure, ChronicRenal Insufficiency, ChronicAlbuminuriaGlomerular Filtration RateHumansAlbuminuriaBrainChronic kidney diseaseCognitionDiabetes mellitusStroke

Identifiers

PMID32857243
PMCPMC9701450
OpenAlexW3081724344

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.