Evidence map›Paper›PMID 32857189›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2020

Long-term clinical results of trabectome surgery in patients with open-angle glaucoma.

Yusuke Kono, Masayuki Kasahara, Kazunori Hirasawa, Tatsuhiko Tsujisawa, Shunsuke Kanayama, Kazuhiro Matsumura, Tetsuya Morita, Nobuyuki Shoji

Abstract read
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In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
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  8. Visual Function After Schlemm's Canal-Based MIGS.Journal of clinical medicine · 2025
    Review
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  11. Review
  12. Five-year outcomes of ab interno Xen 45 gel stent implantation.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
  13. Article
  14. Favorable effect of ripasudil use on surgical outcomes of microhook ab interno trabeculotomy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Article
  15. Review
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  19. Risk of surgical failure and hemorrhagic complications associated with antithrombotic medication in glaucoma surgery.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
    Article
  20. Characteristics of glaucoma patients with intraocular pressure elevation early after trabectome surgery.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yusuke KonoDepartment of Ophthalmology, Kitasato University Graduate School of Medical Sciences, 1-15-1 Kitasato, Minami, Sagamihara, Kanagawa, 252-0374, Japan.
Masayuki KasaharaDepartment of Ophthalmology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Kazunori HirasawaDepartment of Ophthalmology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Tatsuhiko TsujisawaDepartment of Ophthalmology, Kitasato University Graduate School of Medical Sciences, 1-15-1 Kitasato, Minami, Sagamihara, Kanagawa, 252-0374, Japan.
Shunsuke KanayamaDepartment of Ophthalmology, Kitasato University Graduate School of Medical Sciences, 1-15-1 Kitasato, Minami, Sagamihara, Kanagawa, 252-0374, Japan.
Kazuhiro MatsumuraDepartment of Ophthalmology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Tetsuya MoritaDepartment of Ophthalmology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.
Nobuyuki ShojiDepartment of Ophthalmology, Kitasato University Graduate School of Medical Sciences, 1-15-1 Kitasato, Minami, Sagamihara, Kanagawa, 252-0374, Japan. nshoji@kitasato-u.ac.jp.ORCID http://orcid.org/0000-0002-3719-0376
Kitasato University · JPMinamiaoyama Eye Clinic · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the 72-month clinical results of trabectome surgery (TOM) in patients with primary open-angle glaucoma (POAG), secondary OAG and childhood glaucoma.

methodA total of 305 eyes from 249 glaucoma patients were analyzed in the current retrospective single-center study. Kaplan-Meier analysis was performed using three criteria: criterion A (postoperative intraocular pressure [IOP] ≤ 21 mmHg and ≥ 20% reduction from baseline IOP); criterion B (postoperative IOP ≤ 18 mmHg and ≥ 20% reduction from baseline IOP); and criterion C (postoperative IOP ≤ 16 mmHg and ≥ 20% reduction from baseline IOP). The changes in IOP, medication score, success probability, results of the multivariate analysis for success and failure risk factors, and complications were analyzed.

resultsThe baseline IOP in all glaucoma patients decreased from 29.2 ± 9.8 mmHg with a 5.3 ± 1.7 medication score to 16.4 ± 5.8 mmHg (- 43.8%) with a 4.2 ± 1.5 medication score at 72 months (p < 0.01). The success probabilities in all cases for 72 months based on criterion A, B, and C were 44%, 35%, and 17%, respectively. For criterion A, no significant differences were found in the success probability according to the glaucoma subtype for 72 months. The combined surgical procedure significantly decreased the failure risk (hazard ratio [HR]: 0.59). On the other hand, the presence of POAG (HR: 1.6) and a history of past selective laser trabeculoplasty (HR: 2.2) significantly increased failure risk. One patient (0.3%) demonstrated endophthalmitis after TOM but recovered through appropriate treatment.

conclusionAt the 72-month time point, approximately half of the glaucoma patients maintained an IOP ≤ 21 mmHg with ≥ 20% IOP reduction. TOM is a safe surgery but may not yield sufficient IOP reduction in patients who have received SLT or have POAG.

Indexed as

Glaucoma, Open-AngleTrabeculectomyChildHumansIntraocular PressureRetrospective StudiesTonometry, OcularTreatment OutcomeGlaucoma surgeryLong-term resultsMinimally invasive glaucoma surgery (MIGS)Trabectome surgeryTrabeculotomy ab interno

Identifiers

PMID32857189
OpenAlexW3082969211

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.