Evidence map›Paper›PMID 32856865›Full record

ArticleAsian Pacific journal of cancer prevention : APJCP2020

Investigations of Phytoconstituents, Antioxidant and Anti-Liver Cancer Activities of Saueda monoica Forssk Extracted by Microwave-Assisted Extraction.

Ali A A Al-Shawi, Mustafa Fadhil Hameed, Nashwan Hussein Ali, Kawkab Ali Hussein

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Article in Asian Pacific journal of cancer prevention : APJCP, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Ali A A Al-ShawiDepartment of Chemistry, College of Education for Pure Sciences, University of Basrah, Basrah, Iraq.ORCID 0000-0002-0690-4612
Mustafa Fadhil HameedMinistry of Education, General Directorate of Education in Basrah, Basrah, Iraq.ORCID 0000-0002-6915-3369
Nashwan Hussein AliDepartment of Applied Chemistry, College of Applied Sciences, University of Samarra, Iraq.
Kawkab Ali HusseinDepartment of Chemistry, College of Education for Pure Sciences, University of Basrah, Basrah, Iraq.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWild edible plants are good sources for bioactive compounds, vitamins, and minerals with various applications. They can play a role in supporting the immune system and are highly beneficial as resources. Suaeda monoica Forssk is a wild edible plant that grows in Iraq and it's biological activities have not yet reported.

methodsSaueda monoica Forssk bioactive compounds were extracted by a microwave-assisted extraction method using ethanol as a solvent, and its chemical composition was analyzed by GC-MS. The biological activities were evaluated via antioxidant, anti-liver-cancer, antibacterial, and toxicity tests in vitro.

resultsThe results of GC-MS analysis showed that there were about 20 bioactive compounds. The most abundant compound was N,N-Dimethylglycine methyl ester, followed by 9,12,15-Octadecatrienoic acid, n-Hexadecanoic acid, and N,N-Dimethylglycine. The antioxidant activity of the ethanol extract of the plant showed a significant IC50. The extract of S. monoica against liver cancer cells (HCAM) showed significant toxicity. Flow cytometric analysis showed a significant induced apoptosis and cell cycle arrested at G1 phase.

conclusionsThe results indicated the significance of the components of Iraqi S. monoica Forssk by MAE method as a potential food supplement in nutrition systems to prevent liver cancer and enhance the liver's defense against diseases.<br />.

Indexed as

MicrowavesAntineoplastic Agents, PhytogenicAntioxidantsApoptosisCell CycleCell ProliferationChenopodiaceaeHumansLiver NeoplasmsPhytochemicalsPlant ExtractsTumor Cells, CulturedAntineoplastic Agents, PhytogenicAntioxidantsPhytochemicalsPlant ExtractsApoptosisCell cycleLiver cancerNatural antioxidantsSaueda monoica Forssk

Identifiers

PMID32856865
PMCPMC7771932

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.