ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2020
Association of Known Melanoma Risk Factors with Primary Melanoma of the Scalp and Neck.
Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
5 citing papers in PubMed, 13 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
18 authors at 12 institutions in 5 countries.
Renee P WoodSchool of Population and Global Health, The University of Western Australia, Perth, Western Australia, Australia.
Jane S HeyworthSchool of Population and Global Health, The University of Western Australia, Perth, Western Australia, Australia.
Nina S McCarthySchool of Biomedical Sciences, The University of Western Australia, Perth, Western Australia, Australia.
Audrey MauguenDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0003-3236-6093
Marianne BerwickDepartment of Internal Medicine, University of New Mexico Cancer Center, University of New Mexico, Albuquerque, New Mexico.ORCID 0000-0001-5062-2180
Nancy E ThomasDepartment of Dermatology, School of Medicine and Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina.
Michael J MillwardMedical School, The University of Western Australia, Perth, Western Australia, Australia.
Hoda Anton-CulverDepartment of Medicine, University of California, Irvine, California.
Anne E CustSydney School of Public Health and The Melanoma Institute Australia, The University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0002-5331-6370
Terence DwyerGeorge Institute for Global Health Research, University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-2091-7663
Richard P GallagherBritish Columbia Cancer Research Centre and Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0003-2365-0391
Stephen B GruberDepartment of Medical Oncology, City of Hope National Medical Center, Duarte, California.ORCID 0000-0001-8656-7822
Peter A KanetskyDepartment of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.ORCID 0000-0002-5567-9618
Irene OrlowDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.ORCID 0000-0001-6234-6961
Stefano RossoPiedmont Cancer Registry, Turin, Italy.
Eric K MosesMenzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.ORCID 0000-0001-7781-4465
Colin B BeggDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
Sarah V WardSchool of Population and Global Health, The University of Western Australia, Perth, Western Australia, Australia. sarah.ward@uwa.edu.au.
Memorial Sloan Kettering Cancer Center · USThe University of Western Australia · AUCity Of Hope National Medical Center · USMelanoma Institute Australia · AUMoffitt Cancer Center · USNew Mexico Cancer Center · USPiedmont Reference Center for Epidemiology and Cancer Prevention · ITQuest University Canada · CAThe George Institute for Global Health · GBUniversity of California, Irvine · USUniversity of North Carolina at Chapel Hill · USUniversity of Tasmania · AU
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Deborah F. Tate · 1985 to 2026
$201.5M
WOMEN'S CANCERS RESEARCH PROGRAMP30CA118100 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Yolanda Sanchez · 2005 to 2026
$57.1M
Sex Differences in Methylome Alterations and Mutational Burden in Early Stage MelanomaP01CA206980 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI BERWICK, MARIANNE, THOMAS, NANCY E. · 2017 to 2022
$10.1M
Melanoma RAS/BRAF Mutation:Heterogeneity-Risk-PrognosisR01CA112243 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI THOMAS, NANCY E. · 2005 to 2014
$5.4M
A MODEL FOR GENETIC SUSCEPTIBILITY: MELANOMAU01CA083180 · NCI · UNIVERSITY OF NEW MEXICO · PI BERWICK, MARIANNE · 1999 to 2003
$5.2M
Identification of Lethal Melanomas at the Time of DiagnosisR01CA233524 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ANTON-CULVER, HODA A, BEGG, COLIN B · 2020 to 2024
$4.5M
Solar Exposure and Melanoma SurvivalR01CA112524 · NCI · UNIVERSITY OF NEW MEXICO · PI BERWICK, MARIANNE · 2005 to 2009
$2.5M
Epidemiologic Parameters of Rare Cancer Risk FactorsR01CA098438 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI BEGG, COLIN B · 2003 to 2005
$839k
Melanoma Prevention: Using the SunK05CA131675 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI BERWICK, MARIANNE · 2011 to 2015
$795k
Validation of the use of whole-genome amplified DNA in a population-based studyR03CA173806 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI ORLOW, IRENE · 2013 to 2014
$170k
Mutational Analysis of Clonality in Multiple Primary MelanomaR03CA125829 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI ORLOW, IRENE · 2006 to 2007
backgroundScalp and neck (SN) melanoma confers a worse prognosis than melanoma of other sites but little is known about its determinants. We aimed to identify associations between SN melanoma and known risk genes, phenotypic traits, and sun exposure patterns.
methodsParticipants were cases from the Western Australian Melanoma Health Study (
resultsCompared with other sites, increased odds of SN and facial melanoma were observed in older individuals [SN: OR = 1.28, 95% confidence interval (CI) = 0.92-1.80,
conclusionsDifferences observed between SN melanoma and other sites were also observed for facial melanoma. Factors previously associated with the broader head and neck region, notably older age, may be driven by the facial subregion. A novel finding was the association of IMPACT: Understanding the epidemiology of site-specific melanoma will enable tailored strategies for risk factor reduction and site-specific screening campaigns.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Association of Known Melanoma Risk Factors with Primary Melanoma of the Scalp and Neck. · full record | OpenQuestion