ReviewReviews in medical virology2021
Vitamin D and Covid-19: From potential therapeutic effects to unanswered questions.
Review in Reviews in medical virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Effect of vitamin D supplementation on clinical outcomes in adult patients with COVID-19: A GRADE-assessed systematic review and meta-analysis of randomized controlled trials.Pharmacology research & perspectives · 2024Pooled it
- Positive Effects of Vitamin D Supplementation in Patients Hospitalized for COVID-19: A Randomized, Double-Blind, Placebo-Controlled Trial.Nutrients · 2022Trial
- Evaluation of the Effects of an Immune-Boosting Food Supplement on the Severity and Frequency of Pediatric Respiratory Tract Infections: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.Children (Basel, Switzerland) · 2026Article
- Article
- Vitamin D Regulation of Immune Function.Current osteoporosis reports · 2022Review
- Association of vitamin D status with COVID-19 disease severity in pediatric patients: A retrospective observational study.Health science reports · 2022Article
- SARS-CoV-2 and Coronavirus Disease Mitigation: Treatment Options, Vaccinations and Variants.Pathogens (Basel, Switzerland) · 2022Review
- Vitamin D supplementation and COVID-19 risk: a population-based, cohort study.Journal of endocrinological investigation · 2022Article
- Exploration of blood-derived coding and non-coding RNA diagnostic immunological panels for COVID-19 through a co-expressed-based machine learning procedure.Frontiers in immunology · 2022Article
- Micronutrient therapy and effective immune response: a promising approach for management of COVID-19.Infection · 2021Review
- Diet, Probiotics and Their Impact on the Gut Microbiota during the COVID-19 Pandemic.Nutrients · 2021Review
- The role of vitamin D in reducing SARS-CoV-2 infection: An update.International immunopharmacology · 2021Review
- COVID-19-related thyroid conditions (Review).Experimental and therapeutic medicine · 2021Review
- Bad Prognosis in Critical Ill Patients with COVID-19 during Short-Term ICU Stay regarding Vitamin D Levels.Nutrients · 2021Article
- Pharmacological Effects of Selected Medicinal Plants and Vitamins Against COVID-19.Journal of food and nutrition (Frisco, Tex.) · 2021Article
- Association of Calcitriol Supplementation with Reduced COVID-19 Mortality in Patients with Chronic Kidney Disease: A Population-Based Study.Biomedicines · 2021Article
- A genetic insight into vitamin D binding protein and COVID-19.Medical hypotheses · 2021Article
- COVID-19: Characteristics and Therapeutics.Cells · 2021Review
- Association of Vitamin D, Zinc and Selenium Related Genetic Variants With COVID-19 Disease Severity.Frontiers in nutrition · 2021Article
- Coronavirus disease 2019 as a syndemic.Reviews in medical virology · 2021Article
Corrections and comments
- Commented on by
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Evidence suggests that vitamin D supplementation could potentially be effective either in treatment or prevention of coronavirus disease 2019 (Covid-19). Indeed, several studies and trials have begun to investigate the impact of vitamin D supplementation on patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In this review, we focus on the potential mechanisms of vitamin D in the pathogenesis of Covid-19. We consider whether deficiency of vitamin D may be one of the underlying biological factors that could explain the excess mortality seen among non-Caucasians. We also raise several important questions which need to be addressed to provide a clear picture of the extent to which vitamin D supplementation may benefit patients with Covid-19, particularly those with underlying risk factors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.