Evidence map›Paper›PMID 32856177›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2021

Radiographic scoliosis angle estimation: spline-based measurement reveals superior reliability compared to traditional COBB method.

Peter Bernstein, Johannes Metzler, Marlene Weinzierl, Carl Seifert, Wadim Kisel, Markus Wacker

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In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Spinopelvic measurements of sagittal balance with deep learning: systematic review and critical evaluation.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022
    Pooled it
  3. Evaluation of the effect of Rigo-Chêneau type brace on adolescent idiopathic scoliosis using computer-aided modeling and 3D surface analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  4. Detecting scoliosis at scale using automated Cobb angle analysis in the UK Biobank.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  5. Article
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  7. Research on a deep learning-based model for measurement of X-ray imaging parameters of atlantoaxial joint.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
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  18. Automatic recognition of whole-spine sagittal alignment and curvature analysis through a deep learning technique.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022
    Article
  19. A deep learning framework for vertebral morphometry and Cobb angle measurement with external validation.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Peter BernsteinDepartment for Orthopaedics and Traumatology, University Comprehensive Spine Center, University Hospital Dresden, Fetscherstrasse 74, 01307, Dresden, Germany. bernspe@gmail.com.ORCID 0000-0003-4051-7154
Johannes MetzlerFaculty of Informatics/Mathematics, HTW Dresden, Friedrich-List-Platz 1, 01069, Dresden, Germany.
Marlene WeinzierlDepartment for Orthopaedics and Traumatology, University Comprehensive Spine Center, University Hospital Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Carl SeifertDepartment for Orthopaedics and Traumatology, University Comprehensive Spine Center, University Hospital Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Wadim KiselDepartment for Orthopaedics and Traumatology, University Comprehensive Spine Center, University Hospital Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Markus WackerFaculty of Informatics/Mathematics, HTW Dresden, Friedrich-List-Platz 1, 01069, Dresden, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

INTRODUCTION AND

objectiveAlthough being standard for scoliosis curve size estimation, COBB angle measurement is well known to be inaccurate, due to a high interobserver variance in end vertebra selection and end plate contour delineation. We propose a stepwise improvement by using a spline constructed from vertebra centroids to resemble spinal curve characteristics more closely. To enhance precision even further, a neural net was trained to detect the centroids automatically. MATERIALS &

methodsVertebra centroids in AP spinal X-ray images of varying quality from 551 scoliosis patients were manually labeled by 4 investigators. With these inputs, splines were generated and the computed curve sizes were compared to the manually measured COBB angles and to the curve estimation obtained from the neural net.

resultsSplines achieved a higher interobserver correlation of 0.92-0.95 compared to manual COBB measurements (0.83-0.92) and showed 1.5-2 times less variance, depending on the anatomic region. This translates into an average of 1° of interobserver measurement deviation for spline-based curve estimation compared to 3°-8° for COBB measurements. The neural net was even more precise and achieved mean deviations below 0.5°.

conclusionIn conclusion, our data suggest an advantage of spline-based automated measuring systems, so further investigations are warranted to abandon manual COBB measurements.

Indexed as

ScoliosisHumansObserver VariationRadiographyReproducibility of ResultsSpineAutomatic measurementCOBB angleDeep learningLow image qualityRadiographicScoliosis curve

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.