Evidence map›Paper›PMID 32855893›Full record

ArticleTranslational vision science & technology2020

Effect of Disease Progression on the PRL Location in Patients With Bilateral Central Vision Loss.

Luminita Tarita-Nistor, Mark S Mandelcorn, Efrem D Mandelcorn, Samuel N Markowitz

Open access · goldAbstract read
In one paragraph

Article in Translational vision science & technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Binocularity Principles of PRL Development in Patients With Macular Disease.Investigative ophthalmology & visual science · 2022
    Article
  5. Binocular visual function and fixational control in patients with macular disease: A review.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Luminita Tarita-NistorDonald K Johnson Eye Institute, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.
Mark S MandelcornDonald K Johnson Eye Institute, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.
Efrem D MandelcornDonald K Johnson Eye Institute, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.
Samuel N MarkowitzDonald K Johnson Eye Institute, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.
University Health Network · CAKrembil Research InstituteUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the effect of disease progression on the monocular preferred retinal locus (PRL) of the better eye (BE) and worse eye (WE) of patients with central vision loss. Methods: Fifty-one patients with bilateral macular diseases were included. The monocular PRL was recorded for each eye ( Results: Scotoma size increased significantly in both eyes. The PRL distance from the former fovea increased significantly from visit 1 to visit 2 in the BE, but not in the WE. The polar angle was relatively stable in both visits for the BE. The change in PRL location in the BE was predicted only by the PRL distance from the former fovea in visits 1 and 2, but not by polar angle or scotoma size. For the WE, the change in PRL location depended on the change in PRL location in the BE, rather than on measurements made on that eye. Conclusions: Disease progression affects monocular PRL location differently in the 2 eyes. The results suggest a recalibration of the oculomotor system with its reference at the PRL from the BE. Translational Relevance: These findings are important for deciding the course of treatment and/or for developing rehabilitation techniques focusing on PRL relocation.

Indexed as

ScotomaVisual Field TestsDisease ProgressionHumansVisual AcuityVisual Fieldsage-related macular degenerationbinocular visioncentral vision losspreferred retinal locus

Identifiers

PMID32855893
PMCPMC7422864
OpenAlexW3046241969

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.