Evidence map›Paper›PMID 32855857›Full record

ArticleTranslational vision science & technology2020

Chromatic Pupilloperimetry Measures Correlate With Visual Acuity and Visual Field Defects in Retinitis Pigmentosa Patients.

Ifat Sher, Yisroel Tucker, Maya Gurevich, Amit Hamburg, Ettel Bubis, Jonathan Kfir, Shlomit Zorani, Estela Derazne, Alon Skaat, Ygal Rotenstreich

Open access · goldAbstract read
In one paragraph

Article in Translational vision science & technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Thicker macula in asymptomaticAlzheimer's & dementia (Amsterdam, Netherlands) · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ifat SherGoldschleger Eye Institute, Sheba Medical Center, Tel-Hashomer, Israel.
Yisroel TuckerGoldschleger Eye Institute, Sheba Medical Center, Tel-Hashomer, Israel.
Maya GurevichGoldschleger Eye Institute, Sheba Medical Center, Tel-Hashomer, Israel.
Amit HamburgGoldschleger Eye Institute, Sheba Medical Center, Tel-Hashomer, Israel.
Ettel BubisGoldschleger Eye Institute, Sheba Medical Center, Tel-Hashomer, Israel.
Jonathan KfirGoldschleger Eye Institute, Sheba Medical Center, Tel-Hashomer, Israel.
Shlomit ZoraniGoldschleger Eye Institute, Sheba Medical Center, Tel-Hashomer, Israel.
Estela DerazneSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Alon SkaatGoldschleger Eye Institute, Sheba Medical Center, Tel-Hashomer, Israel.
Ygal RotenstreichGoldschleger Eye Institute, Sheba Medical Center, Tel-Hashomer, Israel.
Tel Aviv University · ILSheba Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate the ability of chromatic pupilloperimetry to identify visual field (VF) defects in patients with retinitis pigmentosa (RP) and to test the correlation between pupilloperimetry impairment and retinal structural and functional measures. Methods: The pupil responses of 10 patients with RP (mean age, 41.3 ± 16.2 years) and 32 healthy age-similar controls (mean age, 50.7 ± 15.5 years) for 54 focal blue and red stimuli presented in a 24-2 VF were recorded. The pupilloperimetry measures were correlated with Humphrey VF mean deviation, best-corrected visual acuity, and ellipsoid zone area. Results: Substantially lower percentage of pupil contraction and maximal pupil contraction velocity (MCV) were recorded in patients with RP throughout the VF in response to blue and red stimuli. The mean absolute deviation (MADEV) in the latency of MCV (LMCV) was significantly larger in patients compared with controls for blue and red stimuli ( Conclusions: The chromatic pupilloperimetry measures significantly correlated with retinal function and structure in patients with RP at various disease stages. Translational Relevance: Chromatic pupilloperimetry may enable objective assessment of visual field defects and visual acuity in RP.

Indexed as

Retinitis PigmentosaVisual FieldsAdultAgedHumansMiddle AgedReflex, PupillaryVisual AcuityVisual Field Testschromatic pupilloperimetryperimetrypupillary light reflexretinitis pigmentosa

Identifiers

PMID32855857
PMCPMC7422758
OpenAlexW3040873786

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.