Evidence map›Paper›PMID 32855848›Full record

ArticleTranslational vision science & technology2020

Lamivudine Inhibits

Kazuhisa Yamada, Hiroki Kaneko, Hideyuki Shimizu, Ayana Suzumura, Rina Namba, Kei Takayama, Seina Ito, Masataka Sugimoto, Hiroko Terasaki

Open access · goldAbstract read
In one paragraph

Article in Translational vision science & technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  3. A multi-omics analysis of human fibroblasts overexpressing anbioRxiv : the preprint server for biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Kazuhisa YamadaDepartment of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Hiroki KanekoDepartment of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Hideyuki ShimizuDepartment of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Ayana SuzumuraDepartment of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Rina NambaDepartment of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Kei TakayamaDepartment of Ophthalmology, National Defense Medical College, Japan.
Seina ItoDepartment of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Masataka SugimotoDepartment of Mechanism of Aging, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.
Hiroko TerasakiDepartment of Ophthalmology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Nagoya University · JPNational Center for Geriatrics and Gerontology · JPNational Defense Medical College · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Accumulation of the long noncoding Methods: Cultured human RPE cells and in vivo mouse RPE cells were transfected with an in vitro-transcribed Results: Treatment with 3TC markedly reduced Conclusions: Our data suggest that Translational Relevance: Further verifying this study leads to potential targets for age-related macular degeneration therapy.

Indexed as

LamivudineRetinal Pigment EpitheliumAnimalsAnti-Inflammatory AgentsInflammasomesMiceRNAAnti-Inflammatory AgentsInflammasomesLamivudineRNAage-related macular degenerationlamivudineNLRP3 inflammasomeretinal pigment epitheliumsenescence

Identifiers

PMID32855848
PMCPMC7422901
OpenAlexW3038727963

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.