Evidence map›Paper›PMID 32855766›Full record

ReviewOxidative medicine and cellular longevity2020

Beta-Blockers and Berberine: A Possible Dual Approach to Contrast Neuroblastoma Growth and Progression.

Maura Calvani, Angela Subbiani, Gennaro Bruno, Claudio Favre

Open access · hybridAbstract readReview
In one paragraph

Review in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Maura CalvaniDepartment of Paediatric Haematology-Oncology, A. Meyer University Children's Hospital, Florence, Italy.ORCID https://orcid.org/0000-0003-0750-4706
Angela SubbianiDepartment of Paediatric Haematology-Oncology, A. Meyer University Children's Hospital, Florence, Italy.ORCID https://orcid.org/0000-0001-7184-0734
Gennaro BrunoDepartment of Paediatric Haematology-Oncology, A. Meyer University Children's Hospital, Florence, Italy.ORCID https://orcid.org/0000-0001-6252-3825
Claudio FavreDepartment of Paediatric Haematology-Oncology, A. Meyer University Children's Hospital, Florence, Italy.ORCID https://orcid.org/0000-0003-1770-2423
Meyer Children's Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of nutraceuticals during cancer treatment is a long-lasting debate. Berberine (BBR) is an isoquinoline quaternary alkaloid extracted from a variety of medicinal plants. BBR has been shown to have therapeutic effects in different pathologies, particularly in cancer, where it affects pathways involved in tumor progression. In neuroblastoma, the most common extracranial childhood solid tumor, BBR, reduces tumor growth by regulating both stemness and differentiation features and by inducing apoptosis. At the same time, the inhibition of

Indexed as

Disease ProgressionAdrenergic beta-AntagonistsAnimalsBerberineBrain NeoplasmsCell ProliferationDietary SupplementsHumansNeuroblastomaAdrenergic beta-AntagonistsBerberine

Identifiers

PMID32855766
PMCPMC7443044
OpenAlexW3048563745

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.