ArticleExperimental and therapeutic medicine2020
Mild AKI is associated with mortality of patients who underwent cardiopulmonary bypass surgery.
Article in Experimental and therapeutic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 11 citations in OpenAlex.
- Explainable machine learning models for early prediction of acute kidney injury after cardiac surgery.International urology and nephrology · 2026Article
- A Mild Increase in Serum Creatinine after Surgery Is Associated with Increased Mortality.Journal of clinical medicine · 2024Article
- Preoperative endothelial dysfunction for the prediction of acute kidney injury after cardiac surgery using cardiopulmonary bypass: a pilot study based on a second analysis of the MONS study.Perioperative medicine (London, England) · 2024Article
- Risk Factors for Acute Kidney Injury Following Cardiac Surgery and Performance of Leicester Score in a Spanish Cohort.Journal of clinical medicine · 2022Article
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2 authors at 1 institution in 1 country.
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Abstract
Acute kidney injury (AKI) stage I is the most common stage of AKI observed among patients who underwent cardiac surgery with cardiopulmonary bypass (CPB). The relationship between AKI stage I and mortality requires further investigation. Patients aged 18 years or older who underwent cardiac surgery with CPB between July 1, 2013 and May 31, 2014, were reviewed in the present study. Patients were dichotomized into: i) The AKI stage I group, and ii) the non-AKI group. The primary measured characteristic in the present study was the relationship between AKI and mortality. Kaplan-Meier survival analyses were taken to obtain survival curves. A total of 1,846 patients were included in this present study. The mean age was 51.76±13.56 years. A total of 1,508 patients did not develop AKI and 338 developed AKI stage I. The mean follow-up period among survivors was 9.95±3.45 months. Kaplan-Meier survival analyses showed that patients with AKI stage I were at an increased mortality risk (P<0.0001). In multivariate Cox regression analysis, AKI stage I remained independently associated with a reduced survival. Using a subgroup analysis, patients with non-recovery AKI (defined as non-recovery AKI if the serum level does not return before surgery) had a higher mortality rate than patients with recovery AKI (P<0.0001). AKI stage I is the most common form of AKI and it is independently related to all-cause mortality in patients who underwent cardiovascular surgery with cardiopulmonary bypass.
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