Evidence map›Paper›PMID 32855439›Full record

ArticleLeukemia2020

Anti-SARS-CoV-2 antibody response in patients with chronic lymphocytic leukemia.

Lindsey E Roeker, David A Knorr, Melissa S Pessin, Lakshmi V Ramanathan, Meghan C Thompson, Lori A Leslie, Andrew D Zelenetz, Anthony R Mato

Registry-linked trialAbstract read
In one paragraph

Article in Leukemia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04878822 (Prospective, Cohort, Non-interventional, Single-center Clinical Study of Immune Response Status to SARS-CoV-2 / Covid-19 Vaccination in Patients With Haematological Malignancies.), which is not on this map. Cited by 62 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04878822 unknown statusnot on this mapstarted 2021, after this paper: background citation

Prospective, Cohort, Non-interventional, Single-center Clinical Study of Immune Response Status to SARS-CoV-2 / Covid-19 Vaccination in Patients With Haematological Malignancies.

TypeobservationalSponsorOspedale di Circolo - Fondazione MacchiRan2021 to 2023Enrolled300ConditionsImmunogenicity, Hematological Malignancies, Covid-19, Vaccine Response Impaired
3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Immunological and clinical efficacy of COVID-19 vaccines in immunocompromised populations: a systematic review.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2022
    Pooled it
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Lindsey E RoekerLeukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. roekerl@mskcc.org.ORCID http://orcid.org/0000-0002-3806-059X
David A KnorrLeukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0002-0766-8914
Melissa S PessinDepartment of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0003-3990-6494
Lakshmi V RamanathanDepartment of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Meghan C ThompsonLeukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Lori A LeslieJohn Theurer Cancer Center at Hackensack University Medical Center, Hackensack, NJ, USA.
Andrew D ZelenetzLymphoma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Anthony R MatoLeukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational SuccessUL1TR001866 · NCATS · ROCKEFELLER UNIVERSITY · PI COLLER, BARRY, KRUEGER, JAMES G · 2016 to 2025
$40.6M
Institutional Career Development CoreKL2TR001865 · NCATS · ROCKEFELLER UNIVERSITY · PI SCHLESINGER, SARAH JANE · 2016 to 2025
$8.7M
Fc-enhanced CD40 agonist antibodies for immune modulation of the tumor microenvironmentK08CA248966 · NCI · ROCKEFELLER UNIVERSITY · PI KNORR, DAVID A. · 2020 to 2022
$636k
NCATS NIH HHS KL2 TR001865NCATS NIH HHS UL1 TR001866NCI NIH HHS K08 CA248966NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAged, 80 and overAntibodies, NeutralizingAntibodies, ViralBetacoronavirusCoronavirus InfectionsCoronavirus Nucleocapsid ProteinsCOVID-19FemaleHumansImmunity, CellularImmunoglobulin GLeukemia, Lymphocytic, Chronic, B-CellMaleMiddle AgedAntibodies, NeutralizingAntibodies, ViralCoronavirus Nucleocapsid ProteinsImmunoglobulin Gnucleocapsid phosphoprotein, SARS-CoV-2Nucleocapsid ProteinsPhosphoproteinsRNA, Viral

Identifiers

PMID32855439
PMCPMC7450257

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.