Evidence map›Paper›PMID 32855220›Full record

ArticleThe European respiratory journal2021

Serum mitochondrial DNA predicts the risk of acute exacerbation and progression of idiopathic pulmonary fibrosis.

Koji Sakamoto, Taiki Furukawa, Yasuhiko Yamano, Kensuke Kataoka, Ryo Teramachi, Anjali Walia, Atsushi Suzuki, Masahide Inoue, Yoshio Nakahara, Changwan Ryu and 2 more

Abstract readLetter
In one paragraph

Article in The European respiratory journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Mitochondrial DNA signals driving immune responses: Why, How, Where?Cell communication and signaling : CCS · 2025
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. The Asthma Risk Gene,Journal of respiratory biology and translational medicine · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Evolving Perspectives on Innate Immune Mechanisms of IPF.Frontiers in molecular biosciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Koji SakamotoDept of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan sakakoji@med.nagoya-u.ac.jp.ORCID 0000-0002-1794-576X
Taiki FurukawaDept of Medical IT Center, Nagoya University Hospital, Nagoya, Japan.
Yasuhiko YamanoDept of Respiratory and Allergy, Tosei General Hospital, Seto, Japan.
Kensuke KataokaDept of Respiratory and Allergy, Tosei General Hospital, Seto, Japan.
Ryo TeramachiDept of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Anjali WaliaSection of Pulmonary, Critical Care, and Sleep Medicine, Yale University School of Medicine, New Haven, CT, USA.
Atsushi SuzukiDept of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Masahide InoueDept of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Yoshio NakaharaDept of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Changwan RyuSection of Pulmonary, Critical Care, and Sleep Medicine, Yale University School of Medicine, New Haven, CT, USA.
Naozumi HashimotoDept of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.ORCID 0000-0003-2337-629X
Yasuhiro KondohDept of Respiratory and Allergy, Tosei General Hospital, Seto, Japan.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Mitochondrial DNA and TLR9 in Pulmonary FibrosisK08HL151970 · NHLBI · YALE UNIVERSITY · PI RYU, CHANGWAN · 2020 to 2024
$840k
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS K08 HL151970
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA, MitochondrialIdiopathic Pulmonary FibrosisAcute DiseaseDisease ProgressionHumansDNA, Mitochondrial

Identifiers

PMID32855220
PMCPMC8177039

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.