Evidence map›Paper›PMID 32855201›Full record

Trial reportBritish journal of sports medicine2020

Arthroscopic partial meniscectomy for a degenerative meniscus tear: a 5 year follow-up of the placebo-surgery controlled FIDELITY (Finnish Degenerative Meniscus Lesion Study) trial.

Raine Sihvonen, Mika Paavola, Antti Malmivaara, Ari Itälä, Antti Joukainen, Juha Kalske, Heikki Nurmi, Jaanika Kumm, Niko Sillanpää, Tommi Kiekara and 6 more

2 registry-linked trialsOpen access · hybridAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in British journal of sports medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 74 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 6 pooled it
15.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00549172 nacompletednot on this map

Efficacy of Arthroscopic Partial Resection for the Degenerative Tear of the Medial Meniscus of a Knee

TypeinterventionalSponsorTampere UniversityRan2007 to 2013Enrolled146ConditionsOsteoarthritis, KneeArmsOperative (partial arthroscopy), Conservative (diagnostic arthroscopy)
NCT01052233 phase4unknown statusnot on this map

Effect of Arthroscopic Partial Resection of Degenerative Meniscus Tear on Development of Knee Osteoarthritis: Which is the Chicken and the Egg?

TypeinterventionalSponsorTampere UniversityRan2010 to 2024Enrolled160ConditionsOsteoarthritis of the Knee, Arthroscopy, Meniscal TearArmsArthroscopic partial meniscectomy, Arthroscopy (diagnostic)
3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 6 syntheses or guidelines pooled it, 129 citations in OpenAlex.

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  6. Meniscal repair: The current state and recent advances in augmentation.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2021
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14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 3 countries.

Raine SihvonenDepartment of Orthopaedics and Traumatology, Pihlajalinna Oyj, Tampere, Pirkanmaa, Finland.
Mika PaavolaDepartment of Orthopedics and Traumatology, Töölö Hospital, Helsinki University Hospital, Helsinki, Uusimaa, Finland.
Antti MalmivaaraCentre for Health and Social Economics - CHESS, National Institute for Health and Welfare, Helsinki, Finland.
Ari ItäläPohjola Hospital, Turku, Finland.
Antti JoukainenDepartment of Orthopaedics and Traumatology, Kuopio University Hospital, Kuopio, Finland.
Juha KalskeDepartment of Orthopedics and Traumatology, Helsinki University Hospital, Helsinki, Finland.
Heikki NurmiDepartment of Orthopedics and Traumatology, Central Finland Central Hospital, Jyväskylä, Finland.
Jaanika KummDepartment of Medicine, Tartu Ulikool, Tartu, Tartumaa, Estonia.
Niko SillanpääMedical Imaging Center, Tampere University Hospital, Tampere, Finland.
Tommi KiekaraMedical Imaging Center, Tampere University Hospital, Tampere, Finland.
Aleksandra TurkiewiczDepartment of Orthopedics, Lund University, Lund, Sweden.
Pirjo ToivonenFinnish Centre for Evidence-Based Orthopedics (FICEBO), University of Helsinki, Helsinki, Finland.
Martin EnglundClinical Epidemiology Unit, Orthopaedics, Lund University, Lund, Sweden.
Simo TaimelaFinnish Centre for Evidence-Based Orthopedics (FICEBO), University of Helsinki, Helsinki, Finland.ORCID http://orcid.org/0000-0001-6755-2983
Teppo L N JärvinenFinnish Centre for Evidence-Based Orthopedics (FICEBO), University of Helsinki, Helsinki, Finland teppo.jarvinen@helsinki.fi.ORCID http://orcid.org/0000-0003-3713-956X
FIDELITY (Finnish Degenerative Meniscus Lesion Study) Investigators
University of Helsinki · FILund University · SETampere University Hospital · FICentral Finland Health Care District · FIFinnish Institute for Health and Welfare · FIHelsinki University Hospital · FIKuopio University Hospital · FITurku City Hospital · FIUniversity of Tartu · EE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the long-term effects of arthroscopic partial meniscectomy (APM) on the development of radiographic knee osteoarthritis, and on knee symptoms and function, at 5 years follow-up.

designMulticentre, randomised, participant- and outcome assessor-blinded, placebo-surgery controlled trial.

settingOrthopaedic departments in five public hospitals in Finland.

participants146 adults, mean age 52 years (range 35-65 years), with knee symptoms consistent with degenerative medial meniscus tear verified by MRI scan and arthroscopically, and no clinical signs of knee osteoarthritis were randomised.

interventionsAPM or placebo surgery (diagnostic knee arthroscopy).

main outcome measuresWe used two indices of radiographic knee osteoarthritis (increase in Kellgren and Lawrence grade ≥1, and increase in Osteoarthritis Research Society International (OARSI) atlas radiographic joint space narrowing and osteophyte sum score, respectively), and three validated patient-relevant measures of knee symptoms and function (Western Ontario Meniscal Evaluation Tool (WOMET), Lysholm, and knee pain after exercise using a numerical rating scale).

resultsThere was a consistent, slightly greater risk for progression of radiographic knee osteoarthritis in the APM group as compared with the placebo surgery group (adjusted absolute risk difference in increase in Kellgren-Lawrence grade ≥1 of 13%, 95% CI -2% to 28%; adjusted absolute mean difference in OARSI sum score 0.7, 95% CI 0.1 to 1.3). There were no relevant between-group differences in the three patient-reported outcomes: adjusted absolute mean differences (APM vs placebo surgery), -1.7 (95% CI -7.7 to 4.3) in WOMET, -2.1 (95% CI -6.8 to 2.6) in Lysholm knee score, and -0.04 (95% CI -0.81 to 0.72) in knee pain after exercise, respectively. The corresponding adjusted absolute risk difference in the presence of mechanical symptoms was 18% (95% CI 5% to 31%); there were more symptoms reported in the APM group. All other secondary outcomes comparisons were similar.

conclusionsAPM was associated with a slightly increased risk of developing radiographic knee osteoarthritis and no concomitant benefit in patient-relevant outcomes, at 5 years after surgery.

trial registrationClinicalTrials.gov (NCT01052233 and NCT00549172).

Indexed as

AdultAgedArthroscopyDisease ProgressionFinlandFollow-Up StudiesHumansMagnetic Resonance ImagingMeniscectomyMiddle AgedOsteoarthritis, KneePatient Reported Outcome MeasuresPostoperative ComplicationsRadiographyRisk FactorsTibial Meniscus Injuriesmeniscusosteoarthritis

Identifiers

PMID32855201
PMCPMC7606577
OpenAlexW3080210729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.