ArticleAJNR. American journal of neuroradiology2020
Olfactory Bulb Signal Abnormality in Patients with COVID-19 Who Present with Neurologic Symptoms.
Article in AJNR. American journal of neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 5 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 5 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Topographical Distribution of Neuroanatomical Abnormalities Following COVID-19 Invasion : A Systematic Literature Review.Clinical neuroradiology · 2024Pooled it
- Imaging Markers of Neurologic Damage in COVID-19: A Systematic Review.Current medicinal chemistry · 2023Pooled it
- Olfactory system measurements in COVID-19: a systematic review and meta-analysis.Neuroradiology · 2023Pooled it
- A Systematic Review of Imaging Studies in Olfactory Dysfunction Secondary to COVID-19.Academic radiology · 2021Pooled it
- Pooled it
- Self-Reported Parosmia, Phantosmia, and Gustatory Dysfunction Among Adults with Mild-to-Moderate COVID-19: A Cross-Sectional Study in Saudi Arabia.Clinics and practice · 2025Article
- Mapping the Olfactory Brain: A Systematic Review of Structural and Functional Magnetic Resonance Imaging Changes Following COVID-19 Smell Loss.Brain sciences · 2025Review
- A Comprehensive Review of COVID-19-Related Olfactory Deficiency: Unraveling Associations with Neurocognitive Disorders and Magnetic Resonance Imaging Findings.Diagnostics (Basel, Switzerland) · 2024Review
- Clinical and Imaging Evaluation of COVID-19-Related Olfactory Dysfunction.American journal of rhinology & allergy · 2023Article
- MRI evidence of olfactory system alterations in patients with COVID-19 and neurological symptoms.Journal of neurology · 2023Observational
- [Interpretation of the 2021 American Academy of Allergy, Asthma and Immunology expert consensus on the treatment of postinfectious olfactory dysfunction].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2023Article
- Neurological manifestation in COVID-19 disease with neuroimaging studies.American journal of neurodegenerative disease · 2023Review
- Magnetic resonance imaging findings in COVID-19-related anosmia.Turkish journal of medical sciences · 2022Article
- Magnetic Resonance Imaging Confirmed Olfactory Bulb Reduction in Long COVID-19: Literature Review and Case Series.Brain sciences · 2022Article
- Brain Imaging Changes in Patients Recovered From COVID-19: A Narrative Review.Frontiers in neuroscience · 2022Article
- Oral SARS-CoV-2 Inoculation Causes Nasal Viral Infection Leading to Olfactory Bulb Infection: An Experimental Study.Frontiers in cellular and infection microbiology · 2022Article
- Possible Role of Endocannabinoids in Olfactory and Taste Dysfunctions in COVID-19 Patients and Volumetric Changes in the Brain.Chemosensory perception · 2022Article
- Brain imaging in patients with COVID-19: A systematic review.Brain, behavior, & immunity - health · 2021Review
- Reply.AJNR. American journal of neuroradiology · 2021Article
- Post-viral effects of COVID-19 in the olfactory system and their implications.The Lancet. Neurology · 2021Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeUnique among the acute neurologic manifestations of Severe Acute Respiratory Syndrome coronavirus 2, the virus responsible for the coronavirus disease 2019 (COVID-19) pandemic, is chemosensory dysfunction (anosmia or dysgeusia), which can be seen in patients who are otherwise oligosymptomatic or even asymptomatic. The purpose of this study was to determine if there is imaging evidence of olfactory apparatus pathology in patients with COVID-19 and neurologic symptoms. MATERIALS AND
methodsA retrospective case-control study compared the olfactory bulb and olfactory tract signal intensity on thin-section T2WI and postcontrast 3D T2 FLAIR images in patients with COVID-19 and neurologic symptoms, and age-matched controls imaged for olfactory dysfunction.
resultsThere was a significant difference in normalized olfactory bulb T2 FLAIR signal intensity between the patients with COVID-19 and the controls with anosmia (
conclusionsOlfactory bulb 3D T2 FLAIR signal intensity was greater in the patients with COVID-19 and neurologic symptoms compared with an age-matched control group with olfactory dysfunction, and this was qualitatively apparent in 4 of 12 patients with COVID-19. Analysis of these preliminary finding suggests that olfactory apparatus vulnerability to COVID-19 might be supported on conventional neuroimaging and may serve as a noninvasive biomarker of infection.
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