Evidence map›Paper›PMID 32855167›Full record

ArticleBiology open2020

Functionally distinct roles for T and Tbx6 during mouse development.

Amy K Wehn, Deborah R Farkas, Carly E Sedlock, Dibya Subedi, Deborah L Chapman

Open access · goldAbstract read
In one paragraph

Article in Biology open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Amy K WehnDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Deborah R FarkasDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Carly E SedlockDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Dibya SubediDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Deborah L ChapmanDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA dlc7@pitt.edu.ORCID 0000-0002-8695-6243
University of Pittsburgh · US

Funding

Molecular Mechanism of Paraxial Mesoderm FormationR01HD038786 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHAPMAN, DEBORAH L · 2002 to 2006
$1.3M
NICHD NIH HHS R01 HD038786
6 · The paper itself

Abstract

The mouse T-box transcription factors T and Tbx6 are co-expressed in the primitive streak and have unique domains of expression; T is expressed in the notochord, while Tbx6 is expressed in the presomitic mesoderm. T-box factors are related through a shared DNA binding domain, the T-domain, and can therefore bind to similar DNA sequences at least

Indexed as

Embryonic DevelopmentAllelesAnimalsBase SequenceBinding SitesBrachyury ProteinEmbryo, MammalianEnhancer Elements, GeneticFetal ProteinsGene Expression Regulation, DevelopmentalHEK293 CellsHumansLuciferasesMicePhenotypeProtein DomainsBrachyury ProteinFetal ProteinsLuciferasesT-Box Domain ProteinsTbx6 protein, mouseBrachyuryMesodermMouseTT-boxTbx6

Identifiers

PMID32855167
PMCPMC7473639
OpenAlexW3080619075

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.