Evidence map›Paper›PMID 32855160›Full record

ArticleDiabetes care2020

Glucose as the Fifth Vital Sign: A Randomized Controlled Trial of Continuous Glucose Monitoring in a Non-ICU Hospital Setting.

Addie L Fortmann, Samantha R Spierling Bagsic, Laura Talavera, Isabel Maria Garcia, Haley Sandoval, Amiry Hottinger, Athena Philis-Tsimikas

Registry-linked trialOpen access · bronzeAbstract readComment
In one paragraph

Article in Diabetes care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06607224 (Effect of the Use of Continuous Glucose Monitoring Versus Standard Glycemic Control for Insulin Therapy Adjustment and Decision Making in Noncritical Patients with Type 2 Diabetes Hospitalized in Medical and Surgical Wards.), which is not on this map. Cited by 64 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 3 pooled it
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06607224 nacompletednot on this mapstarted 2022, after this paper: background citation

Effect of the Use of Continuous Glucose Monitoring Versus Standard Glycemic Control for Insulin Therapy Adjustment and Decision Making in Noncritical Patients with Type 2 Diabetes Hospitalized in Medical and Surgical Wards.

TypeinterventionalSponsorHospital General Universitario Gregorio MarañonRan2022 to 2024Enrolled40ConditionsDiabetes Mellitus Type 2, HospitalizationArmsExperimental (Decision making guided by CGM)
3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 3 syntheses or guidelines pooled it, 112 citations in OpenAlex.

  1. [Hospital diabetes management (Update 2026)].Wiener klinische Wochenschrift · 2026
    Guideline
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  3. Pooled it
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  13. Observational
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  20. Observational

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Addie L FortmannScripps Whittier Diabetes Institute, San Diego, CA.
Samantha R Spierling BagsicScripps Whittier Diabetes Institute, San Diego, CA.
Laura TalaveraScripps Whittier Diabetes Institute, San Diego, CA.
Isabel Maria GarciaScripps Whittier Diabetes Institute, San Diego, CA.
Haley SandovalScripps Whittier Diabetes Institute, San Diego, CA.
Amiry HottingerScripps Whittier Diabetes Institute, San Diego, CA.
Athena Philis-TsimikasScripps Whittier Diabetes Institute, San Diego, CA tsimikas.athena@scrippshealth.org.ORCID 0000-0002-3986-9630
Scripps Whittier Diabetes Institute · US

Funding

Scripps Translational Science InstituteUL1TR002550 · NCATS · SCRIPPS RESEARCH INSTITUTE, THE · PI TOPOL, ERIC JEFFREY · 2018 to 2022
$28.9M
New York Regional Center for Diabetes Translation Research - Translational Intervention Methodology CoreP30DK111022 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY GONZALEZ · 2016 to 2026
$7.8M
NCATS NIH HHS UL1 TR002550NIDDK NIH HHS P30 DK111022
6 · The paper itself

Abstract

objectiveThe current standard for hospital glucose management is point-of-care (POC) testing. We conducted a randomized controlled trial of real-time continuous glucose monitoring (RT-CGM) compared with POC in a non-intensive care unit (ICU) hospital setting. RESEARCH DESIGN AND

methodsA total of 110 adults with type 2 diabetes on a non-ICU floor received RT-CGM with Dexcom G6 versus usual care (UC). RT-CGM data were wirelessly transmitted from the bedside. Hospital telemetry monitored RT-CGM data and notified bedside nursing of glucose alerts and trends. Standardized protocols were used for interventions.

resultsThe RT-CGM group demonstrated significantly lower mean glucose (M∆ = -18.5 mg/dL) and percentage of time in hyperglycemia >250 mg/dL (-11.41%) and higher time in range 70-250 mg/dL (+11.26%) compared with UC (

conclusionsRT-CGM can be used successfully in community-based hospital non-ICU settings to improve glucose management. Continuously streaming glucose readings may truly be the fifth vital sign.

Identifiers

PMID32855160
PMCPMC7576427
OpenAlexW3082942486

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.