Evidence map›Paper›PMID 32855051›Full record

ArticleAcademic radiology2021

Comparison of Low Dose Performance of Photon-Counting and Energy Integrating CT.

Jayasai R Rajagopal, Faraz Farhadi, Justin Solomon, Pooyan Sahbaee, Babak Saboury, William F Pritchard, Elizabeth C Jones, Ehsan Samei

Open access · greenAbstract read
In one paragraph

Article in Academic radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Obese patient imaging: Potential dose reduction with photon-counting CT.Journal of applied clinical medical physics · 2026
    Article
  7. Article
  8. Article
  9. Article
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  11. Obese patient imaging: improved dose efficiency with photon-counting CT.medRxiv : the preprint server for health sciences · 2025
    Article
  12. Evaluation of ECG-Gated, High-Pitch Thoracoabdominal Angiographies With Dual-Source Photon-Counting Detector Computed Tomography.Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists · 2025
    Article
  13. Clinical applications of portable CT scanners.The British journal of radiology · 2025
    Review
  14. Article
  15. Ultra-low dose computed tomography chestWorld journal of radiology · 2025
    Article
  16. [Advances in multimodal biomedical imaging of small animals].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
    Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jayasai R RajagopalCarl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Department of Radiology, Duke University Medical Center, Durham, North Carolina; Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, 10 Center Drive, Room 1C351, Bethesda, MD 20892. Electronic address: jayasai.rajagopal@duke.edu.
Faraz FarhadiRadiology and Imaging Sciences, Clinical Center, National Institutes of Health, 10 Center Drive, Room 1C351, Bethesda, MD 20892.
Justin SolomonCarl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Clinical Imaging Physics Group, Department of Radiology, Duke University Medical Center, Durham, North Carolina.
Pooyan SahbaeeSiemens Medical Solutions USA, Malvern, Pennsylvania.
Babak SabouryRadiology and Imaging Sciences, Clinical Center, National Institutes of Health, 10 Center Drive, Room 1C351, Bethesda, MD 20892.
William F PritchardCenter for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Maryland.
Elizabeth C JonesRadiology and Imaging Sciences, Clinical Center, National Institutes of Health, 10 Center Drive, Room 1C351, Bethesda, MD 20892.
Ehsan SameiCarl E. Ravin Advanced Imaging Laboratories, Medical Physics Graduate Program, Clinical Imaging Physics Group, Department of Radiology, Duke University Medical Center, Durham, North Carolina. Electronic address: ehsan.samei@duke.edu.
National Institutes of Health Clinical Center · USDuke Medical Center · USDuke University · US

Funding

Center for Interventional OncologyZIDBC011242 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WOOD, BRADFORD J · 2009 to 2025
$18.7M
Translational Development of Photon-Counting CT ImagingZIACL040017 · CLC · CLINICAL CENTER · PI JONES, ELIZABETH C. · 2020 to 2022
$0k
Intramural NIH HHS Z99 CL999999Intramural NIH HHS ZID BC011242
6 · The paper itself

Abstract

RATIONALE AND

objectivesThe purpose of this study was to investigate the potential of photon-counting CT (PCCT) to improve quantitative image quality for low dose imaging compared to energy-integrating detector CT (EID CT). MATERIALS AND

methodsAn investigational scanner (Siemens, Germany) with PCCT and EID CT subsystems was used to compare image quality performance at four dose levels: 1.7, 2, 4, 6 mGy CTDI

resultsWith resolution unaffected by dose in both PCCT and EID CT, PCCT images exhibited 22.1-24.0% improvement in noise across dose levels evaluated. This noise improvement translated into a 29-41% improvement in CNR and 20-36% improvement in detectability index. For iodine contrast, PCCT images had a higher CNR for all combinations of iodine contrast and dose evaluated.

conclusionFor the conditions studied, PCCT exhibited superior image quality compared to EID CT. For iodine detection, PCCT offered a notable advantage with improved CNR at all doses and iodine concentration levels.

Indexed as

IodineTomography, X-Ray ComputedGermanyHumansPhantoms, ImagingPhotonsIodineComputed tomographyImage qualityLow dosePhoton counting

Identifiers

PMID32855051
PMCPMC7902731
OpenAlexW3080817398

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.