Evidence map›Paper›PMID 32855026›Full record

ReviewJournal of photochemistry and photobiology. B, Biology2020

Light-based technologies for management of COVID-19 pandemic crisis.

Caetano P Sabino, Anthony R Ball, Mauricio S Baptista, Tianhong Dai, Michael R Hamblin, Martha S Ribeiro, Ana L Santos, Fábio P Sellera, George P Tegos, Mark Wainwright

Abstract readReview
In one paragraph

Review in Journal of photochemistry and photobiology. B, Biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. The virucidal potential effects of violet-blue light on influenza D virus.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  7. Article
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  9. Article
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  11. A review on indoor environmental quality in sports facilities: Indoor air quality and ventilation during a pandemic.Indoor + built environment : the journal of the International Society of the Built Environment · 2023
    Article
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  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Caetano P SabinoDepartment of Clinical Analysis, Faculty of Pharmaceutical Sciences, University of São Paulo, SP, Brazil; BioLambda, Scientific and Commercial LTD, São Paulo, SP, Brazil. Electronic address: caetano@biolambda.com.
Anthony R BallGAMA Therapeutics LLC, Massachusetts Biomedical Initiatives, Worcester, USA.
Mauricio S BaptistaDepartment of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, SP, Brazil.. Electronic address: baptista@iq.usp.br.
Tianhong DaiWellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Michael R HamblinWellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Laser Research Centre, Faculty of Health Science, University of Johannesburg, Doornfontein, South Africa.
Martha S RibeiroCenter for Lasers and Applications, Nuclear, and Energy Research Institute, National Commission for Nuclear Energy, São Paulo, SP, Brazil.
Ana L SantosGAMA Therapeutics LLC, Massachusetts Biomedical Initiatives, Worcester, USA; Department of Chemistry Rice University, Houston, TX, USA; IdISBA - Fundación de Investigación Sanitaria de las Islas Baleares, Palma, Spain.
Fábio P SelleraDepartment of Internal Medicine, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, SP, Brazil; School of Veterinary Medicine, Metropolitan University of Santos, Santos, Brazil.
George P TegosGAMA Therapeutics LLC, Massachusetts Biomedical Initiatives, Worcester, USA; Micromoria LLC, Marlborough, USA.
Mark WainwrightSchool of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, UK.

Funding

Photodynamic Therapy of Localized InfectionsR01AI050875 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HAMBLIN, MICHAEL R · 2003 to 2017
$4.8M
Antimicrobial blue light inactivation of pathogenic microbesR01AI123312 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI DAI, TIANHONG · 2016 to 2020
$2.6M
Synergistic Photodynamic Therapy for Catherer-Associated Urinary Tract InfectionsR21AI121700 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HAMBLIN, MICHAEL R · 2016 to 2017
$462k
NIAID NIH HHS R01 AI050875NIAID NIH HHS R01 AI123312NIAID NIH HHS R21 AI121700
6 · The paper itself

Abstract

The global dissemination of the novel coronavirus disease (COVID-19) has accelerated the need for the implementation of effective antimicrobial strategies to target the causative agent SARS-CoV-2. Light-based technologies have a demonstrable broad range of activity over standard chemotherapeutic antimicrobials and conventional disinfectants, negligible emergence of resistance, and the capability to modulate the host immune response. This perspective article identifies the benefits, challenges, and pitfalls of repurposing light-based strategies to combat the emergence of COVID-19 pandemic.

Indexed as

LightBetacoronavirusCoronavirus InfectionsCOVID-19HumansInfrared RaysLasers, Solid-StateLow-Level Light TherapyPandemicsPhotosensitizing AgentsPneumonia, ViralSARS-CoV-2Ultraviolet RaysPhotosensitizing Agentsgermicidalphotobiologyphotobiomodulationphotodynamicphotoinactivationultravioletvirucidal

Identifiers

PMID32855026
PMCPMC7435279

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.