Evidence map›Paper›PMID 32854844›Full record

ReviewJournal of the American College of Cardiology2020

Contemporary Management of Severe Acute Kidney Injury and Refractory Cardiorenal Syndrome: JACC Council Perspectives.

Jacob C Jentzer, Azra Bihorac, Samuel B Brusca, Gaspar Del Rio-Pertuz, Kianoush Kashani, Amir Kazory, John A Kellum, Michael Mao, Brad Moriyama, David A Morrow and 5 more

Erratum issuedOpen access · greenAbstract readReview
In one paragraph

Review in Journal of the American College of Cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 72 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 1 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 1 synthesis or guideline pooled it, 124 citations in OpenAlex.

  1. Pooled it
  2. Kidney Failure in Cardiogenic Shock.Circulation. Heart failure · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Observational
  15. Article
  16. Article
  17. Review
  18. Salvianolic Acid B Attenuates Ferroptosis in Acute Kidney Injury by Targeting PRDX5.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  19. Article
  20. Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 2 countries.

Jacob C JentzerDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota; Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota. Electronic address: jentzer.jacob@mayo.edu.
Azra BihoracDivision of Nephrology, Hypertension and Renal Transplantation, University of Florida, Gainesville, Florida.
Samuel B BruscaCritical Care Medicine Department, National Institutes of Health Clinical Center, Bethesda, Maryland.
Gaspar Del Rio-PertuzDepartment of Critical Care Medicine and Center for Critical Care Nephrology, The CRISMA Center, University of Pittsburgh, Pittsburgh, Pennsylvania.
Kianoush KashaniDivision of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota.
Amir KazoryDivision of Nephrology, Hypertension and Renal Transplantation, University of Florida, Gainesville, Florida.
John A KellumDepartment of Critical Care Medicine and Center for Critical Care Nephrology, The CRISMA Center, University of Pittsburgh, Pittsburgh, Pennsylvania.
Michael MaoDivision of Nephrology and Hypertension, Mayo Clinic, Jacksonville, Florida.
Brad MoriyamaDepartment of Critical Care Medicine, Special Volunteer, National Institutes of Health, Bethesda, Maryland.
David A MorrowTIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Hena N PatelDivision of Cardiology, Department of Medicine, University of Chicago, Chicago, Illinois.
Aniket S RaliDivision of Pulmonary, Critical Care and Sleep Medicine, Baylor College of Medicine, Houston, Texas.
Sean van DiepenDepartment of Critical Care Medicine and Division of Cardiology, Department of Medicine, University of Alberta Hospital, Edmonton, Alberta, Canada.
Michael A SolomonCritical Care Medicine Department, National Institutes of Health Clinical Center, Bethesda, Maryland; Cardiovascular Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland.
Critical Care Cardiology Working Group of the Heart Failure and Transplant Section Leadership Council
Mayo Clinic · USNational Institutes of Health · USUniversity of Florida · USUniversity of Pittsburgh · USAlberta Hospital Edmonton · CABaylor College of Medicine · USBrigham and Women's Hospital · USMayo Clinic in Florida · USNational Institutes of Health Clinical Center · USUniversity of Chicago · US

Funding

Integrating data, algorithms and clinical reasoning for surgical risk assessmentR01GM110240 · NIGMS · UNIVERSITY OF FLORIDA · PI BIHORAC, AZRA, RASHIDI, PARISA · 2016 to 2025
$5.1M
Intramural NIH HHS Z99 CL999999
6 · The paper itself

Abstract

Acute kidney injury (AKI) and cardiorenal syndrome (CRS) are increasingly prevalent in hospitalized patients with cardiovascular disease and remain associated with poor short- and long-term outcomes. There are no specific therapies to reduce mortality related to either AKI or CRS, apart from supportive care and volume status management. Acute renal replacement therapies (RRTs), including ultrafiltration, intermittent hemodialysis, and continuous RRT are used to manage complications of medically refractory AKI and CRS and may restore normal electrolyte, acid-base, and fluid balance before renal recovery. Patients who require acute RRT have a significant risk of mortality and long-term dialysis dependence, emphasizing the importance of appropriate patient selection. Despite the growing use of RRT in the cardiac intensive care unit, there are few resources for the cardiovascular specialist that integrate the epidemiology, diagnostic workup, and medical management of AKI and CRS with an overview of indications, multidisciplinary team management, and transition off of RRT.

Indexed as

Disease ManagementSeverity of Illness IndexAcute Kidney InjuryCardiologyCardio-Renal SyndromeHemofiltrationHumansRenal DialysisRenal Replacement TherapyUnited StatesWater-Electrolyte Balanceacute kidney injurycardiorenal syndromedialysisheart failurehemofiltrationrenal replacement therapyultrafiltration

Identifiers

PMID32854844
PMCPMC11032174
OpenAlexW3081402784

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.