ArticleMilitary Medical Research2020
Establishment and effectiveness evaluation of a scoring system for exertional heat stroke by retrospective analysis.
Article in Military Medical Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.
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22 citing papers in PubMed, 38 citations in OpenAlex.
- Ferroptosis in heatstroke: Mechanisms and therapeutic perspectives (Review).International journal of molecular medicine · 2026Review
- Development and external validation of a machine learning-based Cox model for predicting in-hospital survival in classic heatstroke: a multicenter retrospective study.Scientific reports · 2026Article
- Mesenchymal stem cell-derived extracellular vesicles ameliorate heat stroke-induced hippocampal injury and modulate VIM-AS1-associated miR-34a-5p/Per2 signaling.Frontiers in immunology · 2026Article
- Development and validation of the predictive scoring system for 90-day mortality in critical ill patients with exertional heatstroke.Renal failure · 2025Article
- Machine learning model for early prediction of acute kidney injury in heatstroke patients based on the first 24 h hospitalization data.Scientific reports · 2025Article
- Association between serum creatinine levels at emergency admission and outcomes in patients with exertional heat stroke: a multicenter cohort study.World journal of emergency medicine · 2025Article
- Article
- The value of blood lactate and lactate clearance rate in evaluating the prognosis of athletes with heat illness of varying degrees after high-intensity exercise.BMC sports science, medicine & rehabilitation · 2025Article
- A newly proposed heatstroke-induced coagulopathy score in patients with heat illness: A multicenter retrospective study in China.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2024Article
- Development and validation of a risk prediction model for multiple organ dysfunction syndrome secondary to severe heat stroke based on immediate assessment indicators on ICU admission.Frontiers in medicine · 2024Article
- Clinical relevance of neutrophil/lymphocyte ratio combined with APACHEII for prognosis of severe heatstroke.Heliyon · 2023Article
- Hydrophobic aerogel-modified hemostatic gauze with thermal management performance.Bioactive materials · 2023Article
- Glasgow Coma Scale as an Indicator of Patient Prognosis: A Retrospective Study of 257 Patients with Heatstroke from 3 Medical Centers in Guangdong, China.Medical science monitor : international medical journal of experimental and clinical research · 2023Article
- Sequential organ failure assessment score as a predictor of the outcomes of patients hospitalized for classical or exertional heatstroke.Scientific reports · 2022Observational
- Proposal of New Safety Limits for In Vivo Experiments of Magnetic Hyperthermia Antitumor Therapy.Cancers · 2022Article
- Pushing the frontiers of military medical excellence: updates, progress and future needs.Military Medical Research · 2022Article
- ACSL4 contributes to ferroptosis-mediated rhabdomyolysis in exertional heat stroke.Journal of cachexia, sarcopenia and muscle · 2022Article
- Heatstroke-induced coagulopathy: Biomarkers, mechanistic insights, and patient management.EClinicalMedicine · 2022Review
- Establishment and Effectiveness Evaluation of a Scoring System-RAAS (RDW, AGE, APACHE II, SOFA) for Sepsis by a Retrospective Analysis.Journal of inflammation research · 2022Article
- Machine learning-based mortality prediction model for heat-related illness.Scientific reports · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHeat stroke (HS) is a serious, life-threatening disease. However, there is no scoring system for HS so far. This research is to establish a scoring system that can quantitatively assess the severity of exertional heat stroke (EHS).
methodsData were collected from a total of 170 exertional heat stroke (EHS) patients between 2005 and 2016 from 52 hospitals in China. Univariate statistical methods and comparison of the area under the receiver operating characteristic (ROC) curve (AUC) were used to screen exertional heat stroke score (EHSS) parameters, including but not limited body temperature (T), Glasgow Coma Scale (GCS) and others. By comparing the sizes of the AUCs of the APACHE II, SOFA and EHSS assessments, the effectiveness of EHSS in evaluating the prognosis of EHS patients was verified.
resultsThrough screening with a series of methods, as described above, the present study determined 12 parameters - body temperature (T), GCS, pH, lactate (Lac), platelet count (PLT), prothrombin time (PT), fibrinogen (Fib), troponin I (TnI), aspartate aminotransferase (AST), total bilirubin (TBIL), creatinine (Cr) and acute gastrointestinal injury (AGI) classification - as EHSS parameters. It is a 0-47 point system designed to reflect increasing severity of heat stroke. Low (EHSS< 20) and high scores (EHSS> 35) showed 100% survival and 100% mortality, respectively. We found that AUCEHSS > AUCSOFA > AUCAPACHE II.
conclusionA total of 12 parameters - T, GCS, pH, Lac, PLT, PT, Fib, TnI, AST, TBIL, Cr and gastrointestinal AGI classification - are the EHSS parameters with the best effectiveness in evaluating the prognosis of EHS patients. As EHSS score increases, the mortality rate of EHS patients gradually increases.
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