Trial reportBMC psychiatry2020
Effect of high-intensity interval training on cardiorespiratory fitness, physical activity and body composition in people with schizophrenia: a randomized controlled trial.
Trial report in BMC psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Aerobic High Intensity Training on Symptoms, Cognition, Cortical Structure, Substance Use and Metabolic Indices in Patients With Schizophrenia Spectrum Disorder
Moderate-to-Vigorous Intensity Physical Activity as a Tool for Severe Mental Illness Recuperation Process: Study Protocol for a Pragmatic Controlled Clinical Trial (+moviMENT)
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Impact of Structured Physical Exercise Programs (SPEs) on Symptoms and Clinical Outcomes in Schizophrenia: A Systematic Review With Qualitative Synthesis of Randomized Controlled Trials (2015-2025).Actas espanolas de psiquiatria · 2026Pooled it
- Systematic Review and Meta-analysis of Exercise Interventions for Psychotic Disorders: The Impact of Exercise Intensity, Mindfulness Components, and Other Moderators on Symptoms, Functioning, and Cardiometabolic Health.Schizophrenia bulletin · 2024Pooled it
- Unveiling the chain mediation model of sleep quality and fatigue in linking subjective exercise experience to depression in adolescent.PloS one · 2026Article
- Article
- An Experimental Program of Adapted Physical Activity in the Form of Nordic Walking in the Recovery Process of People with Schizophrenia (Preliminary Report).Brain sciences · 2025Article
- A systematic review of passive data for remote monitoring in psychosis and schizophrenia.NPJ digital medicine · 2025Article
- Effects of Pickleball Intervention on the Self-Esteem and Symptoms of Patients with Schizophrenia.Sports (Basel, Switzerland) · 2025Article
- Effects of aerobic training on brain architecture, hippocampal volume, cardiorespiratory parameters, and health-related quality of life among patients with schizophrenia: A systematic review.Indian journal of psychiatry · 2024Review
- "Out-of-Hospital and with Qualified Exercise Professionals": Keys to the CORTEX-SP Physical Exercise Program According to the Experience of the Participants.European journal of investigation in health, psychology and education · 2023Article
- Alterations in inflammatory markers after a 12-week exercise program in individuals with schizophrenia-a randomized controlled trial.Frontiers in psychiatry · 2023Article
- Aerobic exercise in severe mental illness: requirements from the perspective of sports medicine.European archives of psychiatry and clinical neuroscience · 2022Review
- High-intensity interval training may reduce depressive symptoms in individuals with schizophrenia, putatively through improved VOFrontiers in psychiatry · 2022Article
- Study protocol for a pilot high-intensity interval training intervention in inpatient mental health settings: a two-part study using a randomised controlled trial and naturalistic study design.Pilot and feasibility studies · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExercise may improve cardiorespiratory fitness in people with schizophrenia, however, possible condition-specific cardiorespiratory disadvantages, a scarcity of methodologically sound studies, and conflicting results raise questions about the effect of exercise on maximal oxygen uptake (VO
methodsEighty-two patients with schizophrenia were randomly assigned to supervised high-intensity interval training or computer gaming skills training, performed twice a week for 12 weeks. Oxygen uptake was measured directly, during a maximum exercise session on a treadmill. PA level were assessed using ActiGraph accelerometer, and body composition was assessed by bioelectrical impedance. Differences between groups were assessed by analysis of variance using a univariate general linear model.
resultsThere were no significant differences between the groups on any of the cardiorespiratory variables neither at baseline nor after the program. There were also no significant within-group differences in any of the cardiorespiratory fitness variables between the baseline and post-program time points, despite that 61% of the participants performing high-intensity interval training showed a significant increase in workload on the treadmill. However, 47% of the participants in the high-intensity interval training group had a ≥ 5% increase in VO
conclusionsThe intervention did not improve VO
trial registrationClinicalTrials.gov ; NCT02205684 , registered July 2014.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.