ArticleBMC geriatrics2020
Use of antidepressant medications among older adults in European long-term care facilities: a cross-sectional analysis from the SHELTER study.
Article in BMC geriatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Efficacy and safety of antidepressants for pain in older adults: A systematic review and meta-analysis.British journal of clinical pharmacology · 2024Pooled it
- Pooled it
- Prevention of Gastrointestinal Bleeding in Patients Receiving Direct Oral Anticoagulants: A Narrative Review and Practical Framework for Prescribers.Clinics and practice · 2026Review
- Antidepressant prescribing pattern in Croatia: a retrospective, longitudinal study from 2017 to 2022.Croatian medical journal · 2026Article
- Exogenous Melatonin as a Sleep-promoting Agent beyond its Chronobiotic Properties: A Scoping Review of its Effects on Key Sleep-wake Neurotransmitters.Current neuropharmacology · 2026Article
- Prenatal green space exposure and child's cognition: mediation by cord blood IGF1 in the ENVIRONAGE birth cohort.Environment international · 2025Article
- "The association of cardiometabolic diseases and related medications with cognitive performance: a cross-sectional observational study from Central Poland".BMC geriatrics · 2025Observational
- Daily Energy and Protein Intake Requirements to Prevent Body Weight Loss in Elderly Residents of Nursing Homes.Cureus · 2025Article
- The role of TyG index in predicting low left ventricular ejection fraction after acute coronary syndrome.Biomarkers in medicine · 2025Article
- A real-world analysis of antidepressant medications in US veterans aged 60 years and older: a comparative analysis.Journal of comparative effectiveness research · 2025Article
- Emerging Pharmacological Interventions for Chronic Venous Insufficiency: A Comprehensive Systematic Review and Meta-Analysis of Efficacy, Safety, and Therapeutic Advances.Pharmaceutics · 2025Review
- Exceeding the Limits with Nutraceuticals: Looking Towards Parkinson's Disease and Frailty.International journal of molecular sciences · 2024Review
- The 3 Ds: Depression, Dysbiosis, and Clostridiodes difficile.Advances in therapy · 2024Review
- Relationship between the Mediterranean Diet and Vascular Function in Subjects with and without Increased Insulin Resistance.Nutrients · 2024Article
- Knee Extensor Muscle Strength Associated with the Onset of Depression in Older Japanese Women: The Otassha Study.Nutrients · 2024Article
- Inflammatory markers and frailty in home-dwelling elderly, a cross-sectional study.BMC geriatrics · 2024Article
- Retrospective Investigation and Research on Fall Events Among Hospitalized Patients in the Rehabilitation Department.Risk management and healthcare policy · 2024Article
- Frailty index and risk of delirium in hospitalized patients: a two-sample Mendelian randomization study.Frontiers in medicine · 2024Article
- Relationship Between Depression and Falls Among Nursing Home Residents: Protocol for an Integrative Review.JMIR research protocols · 2023Article
- Clinical profile of trazodone users in a multisetting older population: data from the Italian GeroCovid Observational study.European geriatric medicine · 2023Observational
Corrections and comments
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Authors and funding
10 authors at 7 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLate-life depression is common among older adults living in nursing homes (NHs). Over the last 30 years there has been an increase in the rates of prescription of antidepressant medications across all ages, with the largest rise reported in older adults. This study aimed to describe the pattern of antidepressant medication use among NH residents from 7 European countries and Israel and to examine patient and facilities characteristics that may account for it.
methodsWe conducted a cross-sectional analysis of data from the SHELTER study, an observational longitudinal cohort study that collected comprehensive resident data using the interRAI Long-Term Care Facility instrument in 7 European Countries and Israel. Descriptive statistics were used to examine sample characteristics. Potential correlates of antidepressant medication use were identified using multiple logistic regression modeling.
resultsAmong 4023 residents entering the study, 32% had depressive symptoms and nearly half of these individuals used antidepressants. Antidepressant medication use varied by country, with a prevalence in the overall sample of 35.6% (n = 1431). Among antidepressant users, 59.9% were receiving selective serotonin reuptake inhibitors (SSRI). The strongest correlates of antidepressant use included reported diagnosis of anxiety, depression, bipolar disorder, pain, falls and high level of social engagement. Age over 85 years, living in facilities located in rural areas and a diagnosis of schizophrenia reduced the likelihood of being prescribed with an antidepressant.
conclusionsA large proportion of residents in European long-term care facilities receive antidepressant medications. The decision to prescribe antidepressants to NH residents seems to be influenced by both patient and facility characteristics. Future longitudinal studies should evaluate the efficacy and safety of antidepressant use in NHs thus providing evidence for recommendations for clinical practice.
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