Evidence map›Paper›PMID 32854392›Full record

ArticleNutrients2020

Identification of Genetic Factors Underlying the Association between Sodium Intake Habits and Hypertension Risk.

Yu-Jin Kwon, Jung Oh Kim, Jae-Min Park, Ja-Eun Choi, Da-Hyun Park, Youhyun Song, Seong-Jin Kim, Ji-Won Lee, Kyung-Won Hong

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yu-Jin KwonDepartment of Family Medicine, Yongin Severance Hospital, Yonsei University College of Medicine, 363, Dongbaekjukjeon-daero, Giheung-gu, Yongin-si 16995, Korea.ORCID 0000-0002-9021-3856
Jung Oh KimTheragen Bio Co., Ltd., Suwon 16229, Korea.
Jae-Min ParkDepartment of Family Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul 06273, Korea.ORCID 0000-0001-8873-8832
Ja-Eun ChoiTheragen Bio Co., Ltd., Suwon 16229, Korea.
Da-Hyun ParkTheragen Bio Co., Ltd., Suwon 16229, Korea.
Youhyun SongDepartment of Family Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul 06273, Korea.
Seong-Jin KimTheragen Bio Co., Ltd., Suwon 16229, Korea.
Ji-Won LeeDepartment of Family Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul 06273, Korea.ORCID 0000-0002-2666-4249
Kyung-Won HongTheragen Bio Co., Ltd., Suwon 16229, Korea.
Theragen · KRYonsei University · KR

Funding

Ministry of Trade, Industry and Energy (MOTIE), Korea 20002781National Research Foundation of Korea NRF2018R1D1A1B07049223
6 · The paper itself

Abstract

The role of sodium in hypertension remains unresolved. Although genetic factors have a significant impact on high blood pressure, studies comparing genetic susceptibility between people with low and high sodium diets are lacking. We aimed to investigate the genetic variations related to hypertension according to sodium intake habits in a large Korean population-based study. Data for a total of 57,363 participants in the Korean Genome and Epidemiology Study Health Examination were analyzed. Sodium intake was measured by a semi-quantitative food frequency questionnaire. We classified participants according to sodium intake being less than or greater than 2 g/day. We used logistic regression to test single-marker variants for genetic association with a diagnosis of hypertension, adjusting for age, sex, body mass index, exercise, alcohol, smoking, potassium intake, principal components 1, and principal components 2. Significant associations were defined as

Indexed as

Polymorphism, Single NucleotideFemaleGenetic Predisposition to DiseaseHumansHypertensionMaleMiddle AgedPotassium, DietaryRisk FactorsSodium, DietaryPotassium, DietarySodium, Dietaryhypertensionsingle-nucleotide polymorphismsodium intake

Identifiers

PMID32854392
PMCPMC7551216
OpenAlexW3081423691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.