Evidence map›Paper›PMID 32854342›Full record

ArticlePolymers2020

Ciprofloxacin-Collagen-Based Materials with Potential Oral Surgical Applications.

Daniel-Cristian Ioan, Ileana Rău, Mădălina Georgiana Albu Kaya, Nicoleta Radu, Marinela Bostan, Roxana Gabriela Zgârian, Graţiela Teodora Tihan, Cristina-Elena Dinu-Pîrvu, Alina Lupuliasa, Mihaela Violeta Ghica

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Daniel-Cristian IoanDepartment of General Chemistry, Faculty of Applied Chemistry and Materials Science, University POLITEHNICA of Bucharest, 1-7 Gh. Polizu Str., 011061 Bucharest, Romania.
Ileana RăuDepartment of General Chemistry, Faculty of Applied Chemistry and Materials Science, University POLITEHNICA of Bucharest, 1-7 Gh. Polizu Str., 011061 Bucharest, Romania.ORCID 0000-0002-0780-9502
Mădălina Georgiana Albu KayaDepartment of Collagen, National Research and Development Institute for Textile and Leather (INCDTP), Division Leather and Footwear Research Institute, 93 Ion Minulescu Str., 031215 Bucharest, Romania.ORCID 0000-0001-9960-2244
Nicoleta RaduFaculty of Biotechnology, University of Agronomic Sciences and Veterinary Medicine of Bucharest, 54 Marasti Boulevard, 011464 Bucharest, Romania.ORCID 0000-0002-1106-0258
Marinela BostanInstitute of Virology Stefan S. Nicolau, Immunology Centre, 285 Mihai Bravu Avenue, 030304 Bucharest, Romania.ORCID 0000-0003-3050-6486
Roxana Gabriela ZgârianDepartment of General Chemistry, Faculty of Applied Chemistry and Materials Science, University POLITEHNICA of Bucharest, 1-7 Gh. Polizu Str., 011061 Bucharest, Romania.ORCID 0000-0002-2698-2925
Graţiela Teodora TihanDepartment of General Chemistry, Faculty of Applied Chemistry and Materials Science, University POLITEHNICA of Bucharest, 1-7 Gh. Polizu Str., 011061 Bucharest, Romania.
Cristina-Elena Dinu-PîrvuDepartment of Physical and Colloidal Chemistry, Faculty of Pharmacy, University of Medicine and Pharmacy "Carol Davila", 6 Traian Vuia Str., 020956 Bucharest, Romania.
Alina LupuliasaDepartment of Physical and Colloidal Chemistry, Faculty of Pharmacy, University of Medicine and Pharmacy "Carol Davila", 6 Traian Vuia Str., 020956 Bucharest, Romania.
Mihaela Violeta GhicaDepartment of Physical and Colloidal Chemistry, Faculty of Pharmacy, University of Medicine and Pharmacy "Carol Davila", 6 Traian Vuia Str., 020956 Bucharest, Romania.
Universitatea Națională de Știință și Tehnologie Politehnica București · ROCarol Davila University of Medicine and Pharmacy · RONational Research & Development Institute for Textiles and Leather · ROUniversity of Agronomic Sciences and Veterinary Medicine of Bucharest · RO

Funding

Ministry of Education and Research, Romania, from the Institutional Development Fund for Public Universities - FDI 2020 CNFIS-FDI-2020-0604 (MEDEX-III)
6 · The paper itself

Abstract

We report in this paper the synthesis and characterization of a new collagen-based material. This material was obtained in a spongy form and was functionalized with an antibiotic, ciprofloxacin. The targeted applications of these kind of materials concern the post-operative prophylaxis. The in vitro tests (antimicrobial, cytotoxic, drug release) showed that sponges with a concentration of 0.75 g of ciprofloxacin per gram of collagen could be beneficial for the desired applications.

Indexed as

ciprofloxacincollagen-based materialscytotoxicitydrug release

Identifiers

PMID32854342
PMCPMC7563124
OpenAlexW3081127294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.