Evidence map›Paper›PMID 32854327›Full record

ArticleJournal of clinical medicine2020

Association between Left Atrial Deformation and Brain Involvement in Patients with Anderson-Fabry Disease at Diagnosis.

Roberta Esposito, Camilla Russo, Ciro Santoro, Sirio Cocozza, Eleonora Riccio, Regina Sorrentino, Giuseppe Pontillo, Federica Luciano, Massimo Imbriaco, Arturo Brunetti and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Echocardiography in Anderson-Fabry Disease.Reviews in cardiovascular medicine · 2022
    Review
  7. Article
  8. Fabry Disease and the Heart: A Comprehensive Review.International journal of molecular sciences · 2021
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Roberta EspositoDepartement of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.
Camilla RussoDepartment of Advanced Biomedical Sciences, Federico II University Hospital, 80131 Naples, Italy.ORCID 0000-0002-2256-7281
Ciro SantoroDepartment of Advanced Biomedical Sciences, Federico II University Hospital, 80131 Naples, Italy.
Sirio CocozzaDepartment of Advanced Biomedical Sciences, Federico II University Hospital, 80131 Naples, Italy.
Eleonora RiccioDepartment of Public Health, Nephrology Unit, Federico II University Hospital, 80131 Naples, Italy.
Regina SorrentinoDepartment of Advanced Biomedical Sciences, Federico II University Hospital, 80131 Naples, Italy.
Giuseppe PontilloDepartment of Advanced Biomedical Sciences, Federico II University Hospital, 80131 Naples, Italy.
Federica LucianoDepartment of Advanced Biomedical Sciences, Federico II University Hospital, 80131 Naples, Italy.
Massimo ImbriacoDepartment of Advanced Biomedical Sciences, Federico II University Hospital, 80131 Naples, Italy.
Arturo BrunettiDepartment of Advanced Biomedical Sciences, Federico II University Hospital, 80131 Naples, Italy.
Antonio PisaniDepartment of Public Health, Nephrology Unit, Federico II University Hospital, 80131 Naples, Italy.
Federico II University Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnderson-Fabry disease (AFD) can induce both central nervous system white matter lesions (WMLs) and cardiac abnormalities including left atrial (LA) dysfunction. We sought to evaluate the possible interrelations of LA structure and function impairment with the presence of WMLs in AFD patients. Methods 22 AFD patients and 22 controls, matched for age and sex, underwent an echo-Doppler exam including quantification of peak atrial longitudinal strain (PALS). AFD patients underwent also a 3-T brain magnetic resonance imaging with a visual quantification of WMLs by Fazekas' score (FS) on 3D FLAIR images. Results AFD patients had significantly higher left ventricular (LV) mass index (LVMi) and relative wall thickness, and lower PALS compared to controls. Among AFD patients, 9 showed a FS = 0, and 13 a FS > 1. AFD patients with FS ≥ 1 showed lower PALS (29.4 ± 6.7 vs. 37.2 ± 3.9%,

Indexed as

Anderson Fabry diseaseechocardiographyfazekas’ scoreleft atrial strainwhite matter lesions

Identifiers

PMID32854327
PMCPMC7565878
OpenAlexW3080299266

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.