Evidence map›Paper›PMID 32854299›Full record

ReviewInternational journal of molecular sciences2020

Lipophagy and Lipolysis Status in Lipid Storage and Lipid Metabolism Diseases.

Anna Kloska, Magdalena Węsierska, Marcelina Malinowska, Magdalena Gabig-Cimińska, Joanna Jakóbkiewicz-Banecka

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 97 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Autophagy andFrontiers in cellular and infection microbiology · 2026
    Review
  7. Review
  8. Pathogenesis ofFrontiers in cellular and infection microbiology · 2026
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Anna KloskaDepartment of Medical Biology and Genetics, Faculty of Biology, University of Gdańsk, Wita Stwosza 59, 80-308 Gdańsk, Poland.ORCID 0000-0002-5168-0232
Magdalena WęsierskaDepartment of Medical Biology and Genetics, Faculty of Biology, University of Gdańsk, Wita Stwosza 59, 80-308 Gdańsk, Poland.ORCID 0000-0003-4569-6163
Marcelina MalinowskaDepartment of Medical Biology and Genetics, Faculty of Biology, University of Gdańsk, Wita Stwosza 59, 80-308 Gdańsk, Poland.
Magdalena Gabig-CimińskaDepartment of Medical Biology and Genetics, Faculty of Biology, University of Gdańsk, Wita Stwosza 59, 80-308 Gdańsk, Poland.ORCID 0000-0002-2664-8724
Joanna Jakóbkiewicz-BaneckaDepartment of Medical Biology and Genetics, Faculty of Biology, University of Gdańsk, Wita Stwosza 59, 80-308 Gdańsk, Poland.
Gdańsk Medical University · PLInstitute of Biochemistry and Biophysics, Polish Academy of Sciences · PL

Funding

The Faculty of Biology of the University of Gdańsk (task grant no. 531-D130-D693/20) Task grant no. 531-D130-D693/20The Institute of Biochemistry and Biophysics of the Polish Academy of Sciences (task grant no. T-32.1) Task grant no. T-32.1
6 · The paper itself

Abstract

This review discusses how lipophagy and cytosolic lipolysis degrade cellular lipids, as well as how these pathway ys communicate, how they affect lipid metabolism and energy homeostasis in cells and how their dysfunction affects the pathogenesis of lipid storage and lipid metabolism diseases. Answers to these questions will likely uncover novel strategies for the treatment of aforementioned human diseases, but, above all, will avoid destructive effects of high concentrations of lipids-referred to as lipotoxicity-resulting in cellular dysfunction and cell death.

Indexed as

AnimalsAutophagyBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsEnergy MetabolismHomeostasisHumansLipid MetabolismLipid Metabolism DisordersLipolysisMechanistic Target of Rapamycin Complex 1Signal TransductionBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsMechanistic Target of Rapamycin Complex 1lipid dropletslipid metabolismlipid metabolism diseaseslipid storage diseaseslipolysislipophagymTORC1TFEB

Identifiers

PMID32854299
PMCPMC7504288
OpenAlexW3081463887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.