Evidence map›Paper›PMID 32854291›Full record

ArticleInternational journal of environmental research and public health2020

Predictors of Urinary Pyrethroid and Organophosphate Compound Concentrations among Healthy Pregnant Women in New York.

Arin A Balalian, Xinhua Liu, Eva Laura Siegel, Julie Beth Herbstman, Virginia Rauh, Ronald Wapner, Pam Factor-Litvak, Robin Whyatt

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Arin A BalalianDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.ORCID 0000-0001-5928-7833
Xinhua LiuDepartment of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.
Eva Laura SiegelDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.ORCID 0000-0002-4588-8109
Julie Beth HerbstmanColumbia Center for Children's Environmental Health, Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.
Virginia RauhColumbia Center for Children's Environmental Health, Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.
Ronald WapnerDepartment of Obstetrics and Gynecology, Columbia University, New York, NY 10032, USA.
Pam Factor-LitvakDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.
Robin WhyattColumbia Center for Children's Environmental Health, Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.
Columbia University · USCenter for Children · US

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
Supplemental Training in Making Data FAIR and AI/ML ReadyT32ES007322 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Pam R Factor-Litvak, Allison Kupsco · 2000 to 2026
$12.1M
Pre- and Postnatal PBDE Exposure, Thyroid Hormones, and NeurodevelopmentR01ES021806 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HERBSTMAN, JULIE BETH · 2012 to 2016
$2.6M
Training Program in Environmental Life Course EpidemiologyT32ES023772 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FACTOR-LITVAK, PAM R, PERERA, FREDERICA P · 2015 to 2019
$1.3M
Prenatal PAH exposure and genome-wide methylation in a cohort of sibling-pairsR00ES017051 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HERBSTMAN, JULIE BETH · 2011 to 2013
$747k
Endocrine Disruption in Pregnant Women:Thyroid Disruption and Infant DevelopmentR21ES016610 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WAPNER, RONALD · 2009 to 2011
$481k
Prenatal exposure to a mixture of EDCs, maternal thyroid function and child neuroK99ES020364 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HORTON, MEGAN K · 2011 to 2012
$246k
NIEHS NIH HHS P30 ES009089NIEHS NIH HHS T32 ES007322NIH HHS K99 ES020364NIH HHS P30 ES009089NIH HHS R00ES017051NIH HHS R01ES021806NIH HHS R21ES016610NIH HHS T32ES023772
6 · The paper itself

Abstract

Our study aimed to investigate dietary and non-dietary predictors of exposure to pyrethroids, organophosphates pesticides and 2,4-D herbicide in two cohorts of pregnant women in New York City: 153 women from the Thyroid Disruption and Infant Development (TDID) cohort and 121 from the Sibling/Hermanos Cohort(S/H). Baseline data on predictors were collected from the women at time of recruitment. We used three different modeling strategies to address missing data due to biomarker values below the limit of detection (<LOD): (1) logistic regression models with biomarkers categorized as (<median, ≥median); (2) linear regression models, imputing the <LOD values with (LOD/√2); (3) regression models, considering <LOD values as left-censored. Generally, all three models identified similar predictors of exposure. We found that ethnicity, higher income and education predicted higher concentrations of most of the biomarkers in both cohorts. Mothers who consumed processed meat in the TDID cohort, and broiled, barbequed food or burgers in the S/H cohort, tended to have lower concentrations of organophosphates and 2,4-D. The choice of modeling led to a few different predictors identified, and the selection of modeling strategy should be based on the study question.

Indexed as

ChildCohort StudiesEnvironmental ExposureFemaleHumansInsecticidesNew York CityOrganophosphatesPesticidesPregnancyPyrethrinsInsecticidesOrganophosphatesPesticidesPyrethrinslimit of detectionmodeling strategiesorganophosphatepesticidespredictorspyrethroid

Identifiers

PMID32854291
PMCPMC7504694
OpenAlexW3080544983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.