Evidence map›Paper›PMID 32854227›Full record

ArticlePolymers2020

Multicomponent Non-Woven Fibrous Mats with Balanced Processing and Functional Properties.

Tatiana S Demina, Anastasia S Kuryanova, Polina Y Bikmulina, Nadejda A Aksenova, Yuri M Efremov, Zulfar I Khaibullin, Pavel L Ivanov, Nastasia V Kosheleva, Peter S Timashev, Tatiana A Akopova

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Tatiana S DeminaEnikolopov Institute of Synthetic Polymeric Materials, Russian Academy of Sciences (ISPM RAS), 70 Profsoyuznaya st., 117393 Moscow, Russia.ORCID 0000-0003-0271-2231
Anastasia S KuryanovaInstitute for Regenerative Medicine, Sechenov University, 8-2 Trubetskaya st., 119991 Moscow, Russia.
Polina Y BikmulinaInstitute for Regenerative Medicine, Sechenov University, 8-2 Trubetskaya st., 119991 Moscow, Russia.ORCID 0000-0003-2761-5323
Nadejda A AksenovaInstitute for Regenerative Medicine, Sechenov University, 8-2 Trubetskaya st., 119991 Moscow, Russia.
Yuri M EfremovInstitute for Regenerative Medicine, Sechenov University, 8-2 Trubetskaya st., 119991 Moscow, Russia.ORCID 0000-0001-7040-253X
Zulfar I KhaibullinEnikolopov Institute of Synthetic Polymeric Materials, Russian Academy of Sciences (ISPM RAS), 70 Profsoyuznaya st., 117393 Moscow, Russia.
Pavel L IvanovEnikolopov Institute of Synthetic Polymeric Materials, Russian Academy of Sciences (ISPM RAS), 70 Profsoyuznaya st., 117393 Moscow, Russia.
Nastasia V KoshelevaFaculty of Biology, Lomonosov Moscow State University, 12-1, Leninskie Gory, 119234 Moscow, Russia.
Peter S TimashevInstitute for Regenerative Medicine, Sechenov University, 8-2 Trubetskaya st., 119991 Moscow, Russia.ORCID 0000-0001-7773-2435
Tatiana A AkopovaEnikolopov Institute of Synthetic Polymeric Materials, Russian Academy of Sciences (ISPM RAS), 70 Profsoyuznaya st., 117393 Moscow, Russia.
Sechenov University · RUInstitute of Synthetic Polymeric Materials · RULomonosov Moscow State University · RU

Funding

Russian Foundation for Basic Research 18-29-17050
6 · The paper itself

Abstract

The mimicking of the architectonics of native tissue, biodegradable non-woven fibrous mats is one of the most promising forms of scaffolding for tissue engineering. The key properties needed for their successful application in vivo, such as biodegradability, biocompatibility, morphology, mechanical properties, etc., rely on their composition and appropriate 3D structure. A multicomponent system based on biodegradable synthetic (polycaprolactone, oligo-/polylactide) and natural (chitosan, gelatin) polymers, providing the desired processing characteristics and functionality to non-woven mats fabricated via the electrospinning technique, was developed. The solid-state reactive blending of these components provided a one-step synthesis of amphiphilic graft copolymer with an ability to form stable ultra-fine dispersions in chlorinated solvents, which could be successfully used as casting solvents for the electrospinning technique. The synthesized graft copolymer was analyzed with the aim of fractional analysis, dynamic laser scattering, FTIR-spectroscopy and DSC. Casting solution characteristics, namely viscosity, surface tension, and electroconductivity, as well as electrospinning parameters, were studied and optimized. The morphology, chemical structure of the surface layer, mechanical properties and cytocompatibility were analyzed to confirm the appropriate functionality of the formed fibrous materials as scaffolds for tissue engineering.

Indexed as

chitosancytocompatibilityelectrospinninggelatinnon-woven matspolyesterssolvent-free co-extrusion

Identifiers

PMID32854227
PMCPMC7563478
OpenAlexW3080571971

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.