Evidence map›Paper›PMID 32853998›Full record

ArticleDrug and alcohol dependence2020

Using machine learning for real-time BAC estimation from a new-generation transdermal biosensor in the laboratory.

Catharine E Fairbairn, Dahyeon Kang, Nigel Bosch

Registry-linked trialAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05692830 (Towards a Wearable Alcohol Biosensor), which is not on this map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05692830 recruitingnot on this mapstarted 2022, after this paper: background citation

Towards a Wearable Alcohol Biosensor: Examining the Accuracy of BAC Estimates From New-Generation Transdermal Technology Using Large-Scale Human Testing and Machine Learning Algorithms

TypeobservationalSponsorUniversity of Illinois at Urbana-ChampaignRan2022 to 2027Enrolled240ConditionsAlcohol Drinking, Alcohol IntoxicationArmsAlcohol
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Applying Artificial Intelligence to Expand the Measurement Tool Kit in Clinical-Psychological Science: Moving Beyond Self-Reports.Clinical psychological science : a journal of the Association for Psychological Science · 2026
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  19. Accuracy of transdermal alcohol monitoring devices in a laboratory setting.Alcohol and alcoholism (Oxford, Oxfordshire) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Catharine E FairbairnDepartment of Psychology, University of Illinois-Urbana-Champaign, 603 East Daniel Street, Champaign, IL, 61820, USA. Electronic address: cfairbai@illinois.edu.
Dahyeon KangDepartment of Psychology, University of Illinois-Urbana-Champaign, 603 East Daniel Street, Champaign, IL, 61820, USA.
Nigel BoschSchool of Information Sciences, University of Illinois-Urbana-Champaign, 501 East Daniel Street, Champaign, IL, 61820, USA; Department of Educational Psychology, University of Illinois-Urbana-Champaign, 1310 South Sixth Street, Champaign, IL, 61820, USA.

Funding

Examining the Impact of Stress on the Emotionally Reinforcing Properties of Alcohol in Heavy Social Drinkers: A Multimodal Investigation Integrating Laboratory and Ambulatory MethodsR01AA025969 · NIAAA · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Catharine Fairbairn · 2017 to 2026
$3.5M
NIAAA NIH HHS R01 AA025969
6 · The paper itself

Abstract

backgroundTransdermal biosensors offer a noninvasive, low-cost technology for the assessment of alcohol consumption with broad potential applications in addiction science. Older-generation transdermal devices feature bulky designs and sparse sampling intervals, limiting potential applications for transdermal technology. Recently a new-generation of transdermal device has become available, featuring smartphone connectivity, compact designs, and rapid sampling. Here we present initial laboratory research examining the validity of a new-generation transdermal sensor prototype.

methodsParticipants were young drinkers administered alcohol (target BAC = .08 %) or no-alcohol in the laboratory. Participants wore transdermal sensors while providing repeated breathalyzer (BrAC) readings. We assessed the association between BrAC (measured BrAC for a specific time point) and eBrAC (BrAC estimated based only on transdermal readings collected in the immediately preceding time interval). Extra-Trees machine learning algorithms, incorporating transdermal time series features as predictors, were used to create eBrAC.

resultsFailure rates for the new-generation prototype sensor were high (16 %-34 %). Among participants with useable new-generation sensor data, models demonstrated strong capabilities for separating drinking from non-drinking episodes, and significant (moderate) ability to differentiate BrAC levels within intoxicated participants. Differences between eBrAC and BrAC were 60 % higher for models based on data from old-generation vs new-generation devices. Model comparisons indicated that both time series analysis and machine learning contributed significantly to final model accuracy.

conclusionsResults provide favorable preliminary evidence for the accuracy of real-time BAC estimates from a new-generation sensor. Future research featuring variable alcohol doses and real-world contexts will be required to further validate these devices.

Indexed as

Machine LearningAdultAlcohol DrinkingBiosensing TechniquesBreath TestsEthanolFamily CharacteristicsFemaleHumansLaboratoriesMaleSmartphoneEthanolAlcoholBiosensorBlood alcohol concentrationMachine learningReal-timeTransdermal

Identifiers

PMID32853998
PMCPMC7606553

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.