Evidence map›Paper›PMID 32853830›Full record

ArticleJournal of gynecology obstetrics and human reproduction2020

Causes and consequences of fever during pregnancy: A retrospective study in a gynaecological emergency department.

C Egloff, J Sibiude, C Couffignal, L Mandelbrot, O Picone

Open access · bronzeAbstract read
In one paragraph

Article in Journal of gynecology obstetrics and human reproduction, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

C EgloffAssistance Publique-Hôpitaux de Paris APHP.Nord, Service de gynécologie obstétrique, Hôpital Louis Mourier, 178 rue des Renouillers, 92701, Colombes cedex, France; FHU PREMA, France; Université de Paris, Paris, France; INSERM, IAME, UMR 1137, Paris, France. Electronic address: Charles.egloff@gmail.com.
J SibiudeAssistance Publique-Hôpitaux de Paris APHP.Nord, Service de gynécologie obstétrique, Hôpital Louis Mourier, 178 rue des Renouillers, 92701, Colombes cedex, France; FHU PREMA, France; Université de Paris, Paris, France; INSERM, IAME, UMR 1137, Paris, France.
C CouffignalUnité de recherche clinique Paris Nord Val de Seine, URC PNVS, France; Université de Paris, Paris, France; INSERM, IAME, UMR 1137, Paris, France.
L MandelbrotAssistance Publique-Hôpitaux de Paris APHP.Nord, Service de gynécologie obstétrique, Hôpital Louis Mourier, 178 rue des Renouillers, 92701, Colombes cedex, France; FHU PREMA, France; Université de Paris, Paris, France; INSERM, IAME, UMR 1137, Paris, France.
O PiconeAssistance Publique-Hôpitaux de Paris APHP.Nord, Service de gynécologie obstétrique, Hôpital Louis Mourier, 178 rue des Renouillers, 92701, Colombes cedex, France; FHU PREMA, France; Université de Paris, Paris, France; INSERM, IAME, UMR 1137, Paris, France.
Inserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveFever is a very common reason for emergency consultation during pregnancy, and may be associated with maternal, obstetrical and/or fetal adverse outcomes. The aim of this study was to determine the etiologies and to analyze the maternal or fetal complications of fever in pregnancy. STUDY

designA retrospective single center study including all patients who consulted for fever above 38 °C during pregnancy in the gynecological emergency ward from August 2016 to July 2017.

resultsA total of 100 pregnant women who consulted for fever were included. The etiologies were common viral infections (37 %), influenza (21 %), pyelonephritis (11 %), viral gastroenteritis (6%), chorioamnionitis (5%), other (5%). The etiology was unknown for 15 %. Fever was confirmed during consultation in 45/100 patients (45 %). Among patients with confirmed fever, 21/45 (47 %) were hospitalized with a median stay of 3 days [IQR 2-4] and 10/45(22 %) developed fetal or maternal complications. Probabilistic antibiotics were delivered for 34/45, 76 % patients. Only 14/45, 31 % had confirmed bacterial infections. Of the 32 patients with confirmed fever who had no etiologic diagnosis at the initial work-up in the emergency room, 19/32, 59 % received presumptive treatment with amoxicillin against Listeria monocytogenes. None had confirmed listeriosis, and all were probably common viral infections. Among all patients, the complications rate was 13 % and 22 % in the subgroup with fever confirmed at presentation.

conclusionsThis study quantifies the main etiologies and complications of fever during pregnancy. A challenge is to reduce excessive antibiotic use by improving rapid diagnosis of bacterial and viral infections. Prospective studies are needed to target patients at risk of complications in an optimal way and to study new management strategies.

Indexed as

Emergency Service, HospitalFeverAdultAnti-Bacterial AgentsFemaleGastroenteritisHumansInfluenza, HumanListeriosisPregnancyPregnancy Complications, InfectiousPyelonephritisRetrospective StudiesVirus DiseasesAnti-Bacterial AgentsAntibioticsComplicationsEtiologyFeverInfluenzaPregnancy

Identifiers

PMID32853830
PMCPMC7444605
OpenAlexW3080875204

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.