Evidence map›Paper›PMID 32853820›Full record

ArticleThe journal of allergy and clinical immunology. In practice2021

Neutrophil functional profiling and cytokine augmentation for patients with multiple recurrent infections: A case study.

Natalie J Alexander, David J Bozym, Joceyln R Farmer, Priscilla Parris, Adam Viens, Natalie Atallah, Alex Hopke, Allison Scherer, Zeina Dagher, Nicolas Barros and 6 more

Abstract readCase Reports
In one paragraph

Article in The journal of allergy and clinical immunology. In practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Natalie J AlexanderDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Mass.
David J BozymDepartment of Medicine, Massachusetts General Hospital, Boston, Mass.
Joceyln R FarmerDepartment of Medicine, Massachusetts General Hospital, Boston, Mass; Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, Mass; Department of Medicine, Harvard Medical School, Boston, Mass.
Priscilla ParrisDepartment of Medicine, Massachusetts General Hospital, Boston, Mass.
Adam ViensDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Mass.
Natalie AtallahDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Mass; Department of Medicine, Harvard Medical School, Boston, Mass.
Alex HopkeDepartment of Medicine, Harvard Medical School, Boston, Mass; BIOMEMS, Department of Surgery, Massachusetts General Hospital, Boston, Mass; Shriners Hospital for Children, Boston, Mass.
Allison SchererDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Mass; Department of Medicine, Harvard Medical School, Boston, Mass.
Zeina DagherDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Mass; Department of Medicine, Harvard Medical School, Boston, Mass.
Nicolas BarrosDivision of Infectious Diseases, Indiana University School of Medicine, Indianapolis, Ind.
Sally A I KnooihuizenDepartment of Medicine, Massachusetts General Hospital, Boston, Mass.
Rebecca R SaffDepartment of Medicine, Massachusetts General Hospital, Boston, Mass; Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, Mass; Department of Medicine, Harvard Medical School, Boston, Mass.
Mark S PasternackDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Mass; Department of Medicine, Harvard Medical School, Boston, Mass; Pediatric Infectious Disease Unit, Department of Pediatrics, Massachusetts General Hospital, Boston, Mass.
Ryan W ThompsonDepartment of Medicine, Massachusetts General Hospital, Boston, Mass.
Daniel IrimiaDepartment of Medicine, Harvard Medical School, Boston, Mass; BIOMEMS, Department of Surgery, Massachusetts General Hospital, Boston, Mass; Shriners Hospital for Children, Boston, Mass.
Michael K MansourDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Mass; Department of Medicine, Massachusetts General Hospital, Boston, Mass; Department of Medicine, Harvard Medical School, Boston, Mass. Electronic address: mkmansour@mgh.harvard.edu.

Funding

Bio-MicroElectroMechanical Systems Resource CenterP41EB002503 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI TONER, MEHMET · 2004 to 2018
$17.4M
Neutrophil Decision Making in Confined Environments in Health and DiseaseR01GM092804 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI IRIMIA, DANIEL · 2010 to 2022
$4.3M
The role of spleen tyrosine kinase (syk) in neutrophil responses to pathogenic fungi.R01AI132638 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI MANSOUR, MICHAEL K · 2018 to 2021
$1.6M
NIAID NIH HHS R01 AI132638NIBIB NIH HHS P41 EB002503NIGMS NIH HHS R01 GM092804
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CytokinesNeutrophilsFemaleHumansReinfectionYoung AdultCytokines

Identifiers

PMID32853820
PMCPMC7870511

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.