Evidence map›Paper›PMID 32853802›Full record

ArticleActa biomaterialia2020

Synthesis of di- and triacrylamides with tertiary amine cores and their evaluation as monomers in dental adhesive interfaces.

A P P Fugolin, Oscar Navarro, Matthew G Logan, Vincent Huynh, Cristiane M França, Jack L Ferracane, Carmem S Pfeifer

Open access · greenAbstract read
In one paragraph

Article in Acta biomaterialia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 27 citations in OpenAlex.

  1. Enhancing dentin bonding with catechol-based monomers by tailoring photoinitiator systems to overcome radical inhibition.Dental materials : official publication of the Academy of Dental Materials · 2026
    Article
  2. Article
  3. Article
  4. Article
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  6. Bond preservation in caries-affected dentin restored with acrylamide-based adhesives.Dental materials : official publication of the Academy of Dental Materials · 2025
    Article
  7. Evolution of Dental Resin Adhesives-A Comprehensive Review.Journal of functional biomaterials · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. Multi-acrylamides improve bond stability through collagen reinforcement under physiological conditions.Dental materials : official publication of the Academy of Dental Materials · 2024
    Article
  12. Compatibility versus reaction diffusion: Factors that determine the heterogeneity of polymerized adhesive networks.Dental materials : official publication of the Academy of Dental Materials · 2024
    Article
  13. Article
  14. Article
  15. Dentin primer based on a highly functionalized gelatin-methacryloyl hydrogel.Dental materials : official publication of the Academy of Dental Materials · 2023
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

A P P FugolinBiomaterials and Biomechanics, Department of Restorative Dentistry, Oregon Health & Science University, Portland OR 97239, USA.
Oscar NavarroBiomaterials and Biomechanics, Department of Restorative Dentistry, Oregon Health & Science University, Portland OR 97239, USA.
Matthew G LoganBiomaterials and Biomechanics, Department of Restorative Dentistry, Oregon Health & Science University, Portland OR 97239, USA.
Vincent HuynhBiomaterials and Biomechanics, Department of Restorative Dentistry, Oregon Health & Science University, Portland OR 97239, USA.
Cristiane M FrançaBiomaterials and Biomechanics, Department of Restorative Dentistry, Oregon Health & Science University, Portland OR 97239, USA.
Jack L FerracaneBiomaterials and Biomechanics, Department of Restorative Dentistry, Oregon Health & Science University, Portland OR 97239, USA.
Carmem S PfeiferBiomaterials and Biomechanics, Department of Restorative Dentistry, Oregon Health & Science University, Portland OR 97239, USA. Electronic address: Pfeiferc@ohsu.edu.
Oregon Health & Science University · US

Funding

Novel polymeric materials with improved durability in the oral environment: tailoring responses to host and bacterial enzymes with anti-proteolytic and ecology-based antimicrobial approaches.R35DE029083 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI Carmem S. Pfeifer · 2019 to 2026
$8.1M
Tertiary methacrylamides and thiourethane additives as novel dental compositesU01DE023756 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI FERRACANE, JACK L., PFEIFER, CARMEM S. · 2013 to 2017
$2.4M
Smart Self-Sterilizing Dental Composites for Class V RestorationsR01DE026113 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI FERRACANE, JACK L., MERRITT, JUSTIN · 2016 to 2018
$1.2M
Novel dental composites based on methacrylamides and thiourethane oligomersK02DE025280 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI PFEIFER, CARMEM S. · 2016 to 2020
$600k
NIDCR NIH HHS K02 DE025280NIDCR NIH HHS R01 DE026113NIDCR NIH HHS R35 DE029083NIDCR NIH HHS U01 DE023756
6 · The paper itself

Abstract

PURPOSE/

aimIn an attempt to increase the service life of dental adhesive interfaces, more hydrolytically and enzymatically-stable methacrylate alternatives, such as methacrylamides, have been proposed. The aim of this study was to investigate polymerization behavior, as well as mechanical and biological properties of experimental adhesives containing multi-functional acrylamides. MATERIALS AND

methodsMulti-functional acrylamides (N,N-Bis[(3-methylaminoacryl)propyl]methylamine - BMAAPMA, Tris[(2-methylaminoacryl)ethyl]amine - TMAAEA, N,N'-bis(acrylamido) 1,4-diazepane - BAADA, N,N-Diethyl-1,3-bis(acrylamido)propane - DEBAAP) or HEMA (2-Hydroxyethyl methacrylate - control) were added at 40 wt% to UDMA. 0.2 wt% DMPA and 0.4 wt% DPI-PF6 were used as initiators. Polymerization kinetics was followed in real-time in near-IR during photoactivation (320-500 nm, at 630 mW/cm

resultsIn general, the pure methacrylate mixture had higher rate of polymerization (Rp

conclusionsDespite demonstrating high water sorption, the acrylamide-containing materials had similar mechanical and biological properties and enhanced interfacial bond strength stability compared to the methacrylate control.

Indexed as

Composite ResinsDental BondingAminesBisphenol A-Glycidyl MethacrylateDental CementsMaterials TestingMethacrylatesPolymerizationResin CementsAminesBisphenol A-Glycidyl MethacrylateComposite ResinsDental CementsMethacrylatesResin CementsAcrylamideAdhesive interfaceDental restorationsMethacrylateMicro-tensile bond strength

Identifiers

PMID32853802
PMCPMC7530076
OpenAlexW3081478607

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.