Evidence map›Paper›PMID 32853527›Full record

ArticleJournal of dental research2021

Cross-Kingdom Cell-to-Cell Interactions in Cariogenic Biofilm Initiation.

S X Wan, J Tian, Y Liu, A Dhall, H Koo, G Hwang

Open access · greenAbstract read
In one paragraph

Article in Journal of dental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
  5. Article
  6. Review
  7. Metabolic modulation and multi-species interaction:Frontiers in cellular and infection microbiology · 2025
    Article
  8. Arginine inhibits cross-kingdom interactions and synergistic cariogenicity betweenFrontiers in cellular and infection microbiology · 2025
    Article
  9. Article
  10. Microorganisms · 2024
    Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Microorganisms · 2023
    Article
  17. Article
  18. Article
  19. Review
  20. Current and prospective therapeutic strategies: tacklingFrontiers in cellular and infection microbiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

S X WanBiofilm Research Labs, Levy Center for Oral Health, Department of Orthodontics, Divisions of Pediatric Dentistry and Community Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
J TianBiofilm Research Labs, Levy Center for Oral Health, Department of Orthodontics, Divisions of Pediatric Dentistry and Community Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Y LiuBiofilm Research Labs, Levy Center for Oral Health, Department of Orthodontics, Divisions of Pediatric Dentistry and Community Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
A DhallDepartment of Preventive and Restorative Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0001-8950-9994
H KooBiofilm Research Labs, Levy Center for Oral Health, Department of Orthodontics, Divisions of Pediatric Dentistry and Community Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
G HwangBiofilm Research Labs, Levy Center for Oral Health, Department of Orthodontics, Divisions of Pediatric Dentistry and Community Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0001-7277-5639
University of Pennsylvania · USCenter for Innovation · US

Funding

S. mutans-C. albicans interactions synergize the virulence of cariogenic biofilmsR01DE025220 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI KOO, HYUN · 2015 to 2019
$2.0M
Enzymatic approach for targeting mannans/EPS to disrupt cross-kingdom cariogR01DE027970 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI HWANG, GEELSU · 2018 to 2022
$1.7M
NIDCR NIH HHS R01 DE025220NIDCR NIH HHS R01 DE027970
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BiofilmsStreptococcus mutansCandida albicansCell CommunicationStreptococcus gordoniibiophysicsCandida albicanscariesglucansStreptococcus gordoniiStreptococcus mutans

Identifiers

PMID32853527
PMCPMC7755950
OpenAlexW3081844670

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.