ArticleMolecular biology and evolution2021
Genomic Consequences of Long-Term Population Decline in Brown Eared Pheasant.
Article in Molecular biology and evolution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed.
- Repeated genetic adaptation under demographic limits in kiwifruit.The Plant journal : for cell and molecular biology · 2026Article
- Where Can a Threatened Pheasant Persist? Identifying Climate Change Refugia and Mapping Protection Gaps in China.Animals : an open access journal from MDPI · 2026Article
- Population Decline, Inbreeding and Hybridization Shape the Genetic Vulnerability of a Critically Endangered Seabird.Molecular ecology · 2026Article
- Comparative and population genomics analyses of eared pheasants inhabiting highly varying altitudes.BMC genomics · 2026Article
- Tuberculosis Susceptibility and Inbreeding Depression HinderEvolutionary applications · 2026Article
- Pangolin museum genomics reveal the dynamic genetic consequences and extinction risk of the critically endangered Chinese pangolin.Molecular biology and evolution · 2026Article
- A Genomic Method for Combating Wildlife Trafficking: SNP-Based Traceability of Four Endangered Species in China.Animals : an open access journal from MDPI · 2026Article
- Genomic insights into adaptive evolution of Island brown rats (Rattus norvegicus): evidence from Iturup Island in the Russian Far East.BMC ecology and evolution · 2025Article
- Conservation genomics of two endangered buntings reveal genetic diversity before and after severe population declines.BMC biology · 2025Article
- Genomic and population genomic analyses reveal contrasting diversity and demographic histories in a critically endangered and a widespreadPlant diversity · 2025Article
- Genetic Diversity and Phylogenetic Relationships ofAnimals : an open access journal from MDPI · 2025Article
- Dynamics of Deleterious Mutations and Purifying Selection in Small Population Isolates.Molecular biology and evolution · 2025Article
- Genomic insights and the conservation potential of captive breeding: The case of Chinese alligator.Science advances · 2025Article
- The accumulation of harmful genes within the ROH hotspot regions of the Tibetan sheep genome does not lead to genetic load.BMC genomics · 2025Article
- Genomics identifies koala populations at risk across eastern Australia.Ecological applications : a publication of the Ecological Society of America · 2025Article
- Prioritizing Conservation Areas for the Hyacinth Macaw (Evolutionary applications · 2024Article
- Genomic adaptation to small population size and saltwater consumption in the critically endangered Cat Ba langur.Nature communications · 2024Article
- De novo genome of thick-tailed pygmy jerboa Salpingotus crassicauda, Cardiocraniinae, Dipodidae.Scientific data · 2024Article
- Demographic History and Inbreeding in Two Declining Sea Duck Species Inferred From Whole-Genome Sequence Data.Evolutionary applications · 2024Article
- Genomic divergence and mutation load in thePlant diversity · 2024Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Population genetic theory and empirical evidence indicate that deleterious alleles can be purged in small populations. However, this viewpoint remains controversial. It is unclear whether natural selection is powerful enough to purge deleterious mutations when wild populations continue to decline. Pheasants are terrestrial birds facing a long-term risk of extinction as a result of anthropogenic perturbations and exploitation. Nevertheless, there are scant genomics resources available for conservation management and planning. Here, we analyzed comparative population genomic data for the three extant isolated populations of Brown eared pheasant (Crossoptilon mantchuricum) in China. We showed that C. mantchuricum has low genome-wide diversity and a contracting effective population size because of persistent declines over the past 100,000 years. We compared genome-wide variation in C. mantchuricum with that of its closely related sister species, the Blue eared pheasant (C. auritum) for which the conservation concern is low. There were detrimental genetic consequences across all C. mantchuricum genomes including extended runs of homozygous sequences, slow rates of linkage disequilibrium decay, excessive loss-of-function mutations, and loss of adaptive genetic diversity at the major histocompatibility complex region. To the best of our knowledge, this study is the first to perform a comprehensive conservation genomic analysis on this threatened pheasant species. Moreover, we demonstrated that natural selection may not suffice to purge deleterious mutations in wild populations undergoing long-term decline. The findings of this study could facilitate conservation planning for threatened species and help recover their population size.
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