ArticleJCO oncology practice2020
Barriers to the Delivery of Timely, Guideline-Adherent Adjuvant Therapy Among Patients With Head and Neck Cancer.
Article in JCO oncology practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Factors Associated with Head and Neck Cancer Postoperative Radiotherapy Delays: A Systematic Review and Meta-analysis.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2024Pooled it
- Delays Starting Postoperative Radiotherapy Among Head and Neck Cancer Patients: A Systematic Review and Meta-analysis.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2024Pooled it
- Mechanisms Underlying an Enhanced Navigation-Based Intervention to Improve Timely Adjuvant Therapy: A Secondary Analysis of the NDURE Randomized Clinical Trial.JAMA otolaryngology-- head & neck surgery · 2026Trial
- Randomized Trial of Enhanced Versus Standard Navigation to Promote Timely Initiation of Adjuvant Radiotherapy for Head and Neck Cancer.JCO oncology practice · 2025Trial
- Effects of NDURE on Timely Adjuvant Radiotherapy in HNSCC: Subgroup Analysis of an RCT.The Laryngoscope · 2026Article
- A Discharge Summary Prompt Reduces Postoperative Radiotherapy Delay in Head and Neck Cancer Patients.Head & neck · 2026Article
- Barriers and Facilitators to Timely Adjuvant Therapy for Head and Neck Cancer in Rural Care.JAMA otolaryngology-- head & neck surgery · 2026Article
- Exploring Transitions in Care Among Patients With Head and Neck Cancer: A Scoping Review.Head & neck · 2026Article
- Barriers and Timely Postoperative Radiation Therapy in Head and Neck Cancer.JAMA otolaryngology-- head & neck surgery · 2025Article
- Head and Neck Examinations Among Patients Presenting to HRSA-Funded Health Centers in the United States.Journal of public health dentistry · 2025Article
- Transportation barriers, emergency department use, and mortality risk among us adults: a national health interview survey analysis.BMC public health · 2025Article
- Implementation Mapping to Identify Strategies to Increase Timely Postoperative Radiotherapy Initiation for Head/Neck Cancer.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025Article
- Lower survival for surgical treatment of human papillomavirus-related oropharynx cancer at community cancer centers.Journal of the National Cancer Institute · 2025Article
- Impact of Surgeon-Radiation Oncology Dyads in Oral Cavity Cancer Outcomes.Annals of surgical oncology · 2025Article
- Return to Intended Oncological Therapy: State of the Art and Perspectives.Current oncology reports · 2024Review
- Author Reply to Letter by Topkan et al Regarding Delays in Starting Postoperative Radiotherapy.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2024Article
- "Cancer's a demon": a qualitative study of fear and multilevel factors contributing to cancer treatment delays.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
- Patient Navigation for Timely, Guideline-Adherent Adjuvant Therapy for Head and Neck Cancer: A National Landscape Analysis.Journal of the National Comprehensive Cancer Network : JNCCN · 2023Article
- Discharge Disposition After Head and Neck Reconstruction: Effect on Adjuvant Therapy and Outcomes.The Laryngoscope · 2023Article
- Oncologic Significance of Therapeutic Delays in Patients With Oral Cavity Cancer.JAMA otolaryngology-- head & neck surgery · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 5 institutions in 1 country.
Funding
Abstract
purposeDelays initiating guideline-adherent postoperative radiation therapy (PORT) in head and neck squamous cell carcinoma (HNSCC) are common, contribute to excess mortality, and are a modifiable target for improving survival. However, the barriers that prevent the delivery of timely, guideline-adherent PORT remain unknown. This study aims to identify the multilevel barriers to timely, guideline-adherent PORT and organize them into a conceptual model. MATERIALS AND
methodsSemi-structured interviews with key informants were conducted with a purposive sample of patients with HNSCC and oncology providers across diverse practice settings until thematic saturation (n = 45). Thematic analysis was performed to identify the themes that explain barriers to timely PORT and to develop a conceptual model.
resultsIn all, 27 patients with HNSCC undergoing surgery and PORT were included, of whom 41% were African American, and 37% had surgery and PORT at different facilities. Eighteen clinicians representing a diverse mix of provider types from 7 oncology practices participated in key informant interviews. Five key themes representing barriers to timely PORT were identified across 5 health care delivery levels: (1) inadequate education about timely PORT, (2) postsurgical sequelae that interrupt the tight treatment timeline (both intrapersonal level), (3) insufficient coordination and communication during care transitions (interpersonal and health care team levels), (4) fragmentation of care across health care organizations (organizational level), and (5) travel burden for socioeconomically disadvantaged patients (community level).
conclusionThis study provides a novel description of the multilevel barriers that contribute to delayed PORT. Interventions targeting these multilevel barriers could improve the delivery of timely, guideline-adherent PORT and decrease mortality for patients with HNSCC.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.