ReviewEuropean journal of emergency medicine : official journal of the European Society for Emergency Medicine2020
Acute hyperkalemia in the emergency department: a summary from a Kidney Disease: Improving Global Outcomes conference.
Review in European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed, 1 synthesis or guideline pooled it, 124 citations in OpenAlex.
- Interdisciplinary recommendations for recurrent hyperkalaemia: insights from the GUARDIAN-HK European Steering Committee.European heart journal. Cardiovascular pharmacotherapy · 2025Guideline
- Comparison of nebulized salbutamol and glucose-insulin for preventing acute hyperkalemia in liver transplantation: a randomized, double-blind trial.Journal of anesthesia · 2026Trial
- Trial
- AI-enabled electrocardiogram alert for potassium imbalance treatment: a pragmatic randomized controlled trial.Nature communications · 2026Trial
- Assessing the cardiovascular and potassium lowering effects of levalbuterol compared to albuterol: a randomized control trial.Frontiers in cardiovascular medicine · 2025Trial
- Hypertonic glucose vs insulin-dextrose to prevent hypoglycaemia following treatment for hyperkalaemia (HIGH-K): protocol for a double-blind randomized controlled trial.Annals of medicine · 2026Article
- Clinical Outcomes of Hospitalization for Severe Hyperkalemia in the Absence of Life-threatening Manifestations.JMA journal · 2026Article
- Factors associated with acute kidney injury in rhabdomyolysis: Insights from a prospective study.World journal of nephrology · 2026Article
- Comparison of sodium and potassium measurements in the emergency department by point-of-care vs. central laboratory testing : A retrospective analysis.Wiener klinische Wochenschrift · 2026Article
- Real-world treatment of hyperkalemia among patients in emergency department in China (POETRY-E): A study protocol for multicenter, prospective, observational study.The Journal of international medical research · 2026Article
- [Consensus recommendations on the diagnosis and treatment of hyperkalemia of the Austrian Society of Nephrology 2026].Wiener klinische Wochenschrift · 2026Review
- Unpredictable emergency department cardiac arrest: clinical features and the limits of early warning scores and triage acuity.BMC emergency medicine · 2026Article
- Effect of Sodium Zirconium Cyclosilicate Approval on the Management of Acute Hyperkalemia in Japan: Interrupted Time Series Analysis.American journal of nephrology · 2026Article
- What to do with key cardiovascular drugs when kidney function worsens?Clinical kidney journal · 2026Review
- Comprehensive Management of Hyperkalaemia in Patients with Chronic Kidney Disease and Cardiovascular Conditions: Expert Recommendations from Mexico.Cardiac failure review · 2026Review
- DiffuSETS: 12-Lead ECG generation conditioned on clinical text reports and patient-specific information.Patterns (New York, N.Y.) · 2025Article
- Sex Differences in Electrolyte Disturbances Among Diuretic Users According to Renal Function and Age.Drug safety · 2025Article
- Outcomes and Resource Utilization in Hyperkalemic Emergency Department Patients Treated With Patiromer or Sodium Zirconium Cyclosilicate.Journal of the American College of Emergency Physicians open · 2025Article
- Sinus arrest consequence of moderate hyperkalemia: a case report.Oxford medical case reports · 2025Article
- Diuretics in patients with chronic kidney disease.Nature reviews. Nephrology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 11 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hyperkalemia is a common electrolyte disorder observed in the emergency department. It is often associated with underlying predisposing conditions, such as moderate or severe kidney disease, heart failure, diabetes mellitus, or significant tissue trauma. Additionally, medications, such as inhibitors of the renin-angiotensin-aldosterone system, potassium-sparing diuretics, nonsteroidal anti-inflammatory drugs, succinylcholine, and digitalis, are associated with hyperkalemia. To this end, Kidney Disease: Improving Global Outcomes (KDIGO) convened a conference in 2018 to identify evidence and address controversies on potassium management in kidney disease. This review summarizes the deliberations and clinical guidance for the evaluation and management of acute hyperkalemia in this setting. The toxic effects of hyperkalemia on the cardiac conduction system are potentially lethal. The ECG is a mainstay in managing hyperkalemia. Membrane stabilization by calcium salts and potassium-shifting agents, such as insulin and salbutamol, is the cornerstone in the acute management of hyperkalemia. However, only dialysis, potassium-binding agents, and loop diuretics remove potassium from the body. Frequent reevaluation of potassium concentrations is recommended to assess treatment success and to monitor for recurrence of hyperkalemia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.