Evidence map›Paper›PMID 32852722›Full record

ArticleNatural products and bioprospecting2020

Salvia ceratophylla L. from South of Jordan: new insights on chemical composition and biological activities.

Mohammad Sanad Abu-Darwish, Célia Cabral, Zulfigar Ali, Mei Wang, Shabana I Khan, Melissa R Jacob, Surendra K Jain, Babu L Tekwani, Fazila Zulfiqar, Ikhlas A Khan and 3 more

Abstract read
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In one paragraph

Article in Natural products and bioprospecting, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mohammad Sanad Abu-DarwishDepartment of Basic and Applied Sciences, Al-Balqa Applied University, Al-Salt, 19117, Jordan.
Célia CabralCoimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, 3000-548, Coimbra, Portugal. celia.cabral@fmed.uc.pt.
Zulfigar AliNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS, 38677, USA.
Mei WangNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS, 38677, USA.
Shabana I KhanNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS, 38677, USA.
Melissa R JacobNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS, 38677, USA.
Surendra K JainNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS, 38677, USA.
Babu L TekwaniNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS, 38677, USA.
Fazila ZulfiqarNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS, 38677, USA.
Ikhlas A KhanNational Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS, 38677, USA.
Hatem TaifourSchool of Geosciences, University of Edinburgh, 219 Crew Building, King's Buildings, Edinburgh, EH9 3FF, UK.
Lígia SalgueiroCIEPQPF/Faculty of Pharmacy, University of Coimbra, Health Sciences Campus, Azinhaga de S. Comba, 3000-548, Coimbra, Portugal.
Thomas EfferthDepartment of Pharmaceutical Biology, Institute of Pharmaceutical and Biocmedical Sciences, Johannes Gutenberg University, Staudinger Weg 5, 55128, Mainz, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Jordan, Salvia ceratophylla L. is traditionally used in the treatment of cancer, microbial infections, and urinary disorders. This study aimed: (1) to chemically characterize S. ceratophylla essential oil (EO) from South Jordan, by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS); and (2) to evaluate in vitro the cytotoxic, anti-inflammatory, and antiprotozoal activities of the EO, it's predominant components, and the hexane (A), ethyl acetate (B), methanol (C) and crude-methanol extracts (D). The analysis revealed that the EO has 71 compounds, with linalool (54.8%) as main constituent. Only the hexane extract (A) showed some cytotoxic activity against SK-MEL, KB, BT-549, SK-OV-3, LLC-PK1 and VERO cells lines with IC

Indexed as

Anti-inflammatory activityChemical compositionCytotoxicityEssential oilLamiaceaeNeglected diseases

Identifiers

PMID32852722
PMCPMC7520468

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.