Evidence map›Paper›PMID 32852691›Full record

ReviewCurrent hypertension reports2020

Prevention, Diagnosis, and Management of Hypertensive Disorders of Pregnancy: a Comparison of International Guidelines.

Rachel G Sinkey, Ashley N Battarbee, Natalie A Bello, Christopher W Ives, Suzanne Oparil, Alan T N Tita

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Current hypertension reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05676476 (The ACHIEVE Trial), which is not on this map. Cited by 89 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed, 4 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05676476 narecruitingnot on this mapstarted 2023, after this paper: background citation

The ACHIEVE Trial: Achieving Longer Gestation in Preeclampsia Via Antihypertensive Therapy.

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2023 to 2027Enrolled132ConditionsPreeclampsia, Gestational Hypertension, Hypertensive Disorder of PregnancyArmsAntihypertensive treatment
3 · Its place in the literature

Who cites it

89 citing papers in PubMed, 4 syntheses or guidelines pooled it, 190 citations in OpenAlex.

  1. Pooled it
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  3. Pooled it
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  5. Trial
  6. Analytical approaches to evaluating hypertensive disorders of pregnancy.American journal of obstetrics & gynecology MFM · 2023
    Trial
  7. Treatment for Mild Chronic Hypertension during Pregnancy.The New England journal of medicine · 2022
    Trial
  8. Article
  9. Therapeutic Interventions for Preeclampsia: Integrating Placental and Maternal Perspectives.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026
    Review
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29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rachel G SinkeyDepartment of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, University of Alabama at Birmingham, 1700 6th Avenue South, 176F Suite 10270, Birmingham, AL, 35249, USA. rsinkey@uabmc.edu.ORCID 0000-0001-7674-9796
Ashley N BattarbeeDepartment of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, University of Alabama at Birmingham, 1700 6th Avenue South, 176F Suite 10270, Birmingham, AL, 35249, USA.
Natalie A BelloDepartment of Medicine, Division of Cardiology, Columbia College of Physicians and Surgeons, New York, NY, USA.
Christopher W IvesTinsley Harrison Internal Medicine Residency Program, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Suzanne OparilDepartment of Medicine, Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, AL, USA.
Alan T N TitaDepartment of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, University of Alabama at Birmingham, 1700 6th Avenue South, 176F Suite 10270, Birmingham, AL, 35249, USA.
University of Alabama at Birmingham · USColumbia University · US

Funding

Cardiac Manifestations of PreeclampsiaR01HL153382 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BELLO, NATALIE A · 2020 to 2023
$1.6M
Blood Pressure Measurement and Hypertension in PregnancyK23HL136853 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BELLO, NATALIE A · 2018 to 2022
$948k
NHLBI NIH HHS K23 HL136853NHLBI NIH HHS R01 HL153382
6 · The paper itself

Abstract

purpose of reviewHypertensive disorders of pregnancy (HDP)-gestational hypertension, preeclampsia, and eclampsia-are a leading cause of adverse maternal and perinatal outcomes internationally. Prevention, timely diagnosis, and prompt management can reduce associated morbidity. The purpose of this review is to compare international guidelines pertaining to HDP. RECENT

findingsFourteen HDP guidelines were compared relative to guidelines for the United States (US) where the authors practice. Aspirin is universally recommended for high-risk women to reduce preeclampsia risk. Recommended dose and gestational age at initiation vary. Diagnoses of chronic hypertension, gestational hypertension, and preeclampsia in pregnant women are similar, although blood pressure (BP) thresholds for antihypertensive medication initiation and treatment targets vary due to the limitations in high-quality evidence. There are differences among international HDP guidelines related to dose and timing of aspirin initiation, thresholds for antihypertensive medication initiation, and BP targets. However, all guidelines acknowledge the significant morbidity associated with HDP and advocate for timely diagnosis and management to reduce associated morbidity and mortality. More research is needed to understand optimal BP thresholds at which to initiate antihypertensive medication regimens and BP targets in pregnancy.

Indexed as

EclampsiaHypertension, Pregnancy-InducedPre-EclampsiaAntihypertensive AgentsBlood PressureFemaleHumansPregnancyAntihypertensive AgentsChronic hypertensionEclampsiaGestational hypertensionGuidelinesHypertensive disorders of pregnancyPreeclampsia

Identifiers

PMID32852691
PMCPMC7773049
OpenAlexW3081480980

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.