Evidence map›Paper›PMID 32852675›Full record

ArticleAnnals of intensive care2020

Epidural analgesia in ICU chest trauma patients with fractured ribs: retrospective study of pain control and intubation requirements.

Konstantinos Bachoumas, Albrice Levrat, Aurélie Le Thuaut, Stéphane Rouleau, Samuel Groyer, Hervé Dupont, Paul Rooze, Nathanael Eisenmann, Timothée Trampont, Julien Bohé and 32 more

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Annals of intensive care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05506761 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Ultrasound-Guided Continuous Rhomboid Intercostal Block Combined With Sub-Serratus Plane Block Versus Continuous Erector Spinae Plane Block for Analgesia in Patients With Multiple Traumatic Rib Fractures

TypeinterventionalSponsorTanta UniversityRan2022 to 2023Enrolled75ConditionsRib FracturesArmsultrasound-guided erector spinae plane block, ultrasound-guided rhomboid intercostal block combined with sub-serratus plane block
NCT05920109 narecruitingnot on this mapstarted 2023, after this paper: background citation

EffecT of eARly analGesia With Erector Spinae Plane Block to Reduce Ventilation After Severe Chest Trauma: a Randomised Control Open-label Trial.

TypeinterventionalSponsorUniversity Hospital, GrenobleRan2023 to 2027Enrolled400ConditionsSevere Chest TraumaArmsESP block
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 28 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
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  5. Review
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  8. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

42 authors at 20 institutions in 1 country.

Konstantinos BachoumasMédecine Intensive Réanimation, District Hospital Center, La Roche-sur-Yon, France.
Albrice LevratIntensive Care Unit, Regional Hospital Center, Annecy, France.
Aurélie Le ThuautPlateforme de la méthodologie et de la Biostatistique, Direction de la Recherche Clinique, CHU de Nantes, 44093, Nantes Cedex, France.
Stéphane RouleauIntensive Care Unit, Hospital Center, Angoulême, France.
Samuel GroyerIntensive Care Unit, Hospital Center, Montauban, France.
Hervé DupontSurgical Intensive Care Unit, University Hospital, Amiens, France.
Paul RoozeSurgical Intensive Care Unit, University Hospital, Nantes, France.
Nathanael EisenmannIntensive Care Unit, Jean Perrin Center, Clermont-Ferrand, France.
Timothée TrampontIntensive Care Unit, University Hospital, Limoges, France.
Julien BohéUniversity Hospital, Lyon Sud, Lyon, France.
Benjamin RieuSurgical Intensive Care Unit, Gabriel-Montpied University Hospital, Clermont-Ferrand, France.
Jean-Charles ChakarianIntensive Care Unit, Regional Hospital Center, Roanne, France.
Aurélie GodardIntensive Care Unit, Regional Hospital Center, Saint-Brieuc, France.
Laura FredericiIntensive Care Unit, Regional Hospital Center, Sud Francilien, Corbeil-Essone, France.
Stephanie GélinotteIntensive Care Unit, Regional Hospital Center, Dieppe, France.
Aurélie JoretSurgical Intensive Care Unit, University Hospital, Caen, France.
Pascale RoquesIntensive Care Unit, Regional Hospital Center, Cherbourg, France.
Benoit PainvinIntensive Care Unit, Regional Hospital Center, Lorient, France.
Christophe LeroyIntensive Care Unit, Regional Hospital Center, Puy en Velay, France.
Marcel BeneditIntensive Care Unit, Regional Hospital Center, Moulins, France.
Loic DopeuxIntensive Care Unit, Regional Hospital Center, Vichy, France.
Edouard SoumIntensive Care Unit, Regional Hospital Center, Périgueux, France.
Vlad BotocIntensive Care Unit, Regional Hospital Center, Saint-Malo, France.
Muriel FartoukhIntensive Care Unit, University Hospital, Tenon, Paris, France.
Marie-Hélène HausermannIntensive Care Unit, Regional Hospital Center, Aurillac, France.
Toufik KamelIntensive Care Unit, Regional Hospital Center, Orléans, France.
Jean MorinRespiratory Care Unit, University Hospital, Nantes, France.
Roland De VaraxIntensive Care Unit, Regional Hospital Center, Macon, France.
Gaetan PlantefèveIntensive Care Unit, Regional Hospital Center, Argenteuil, France.
Alexandre HerblandIntensive Care Unit, Regional Hospital Center, La Rochelle, France.
Matthieu JabaudonDepartment of Perioperative Medicine, CHU Clermont-Ferrand and GReD, CNRS, UMR 6293, INSERM U1103, Universite Clermont Auvergne, Clermont-Ferrand, France.
Thibault DuburcqMedical Intensive Care Unit, University Hospital, Lille, France.
Christelle SimonIntensive Care Unit, Regional Hospital Center, Versailles, France.
Russell ChabanneNeurological Intensive Care Unit, University Hospital, Clermont-Ferrand, France.
Francis SchneiderMédecine Intensive-Réanimation, Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.
Frederique GansterIntensive Care Unit, Regional Hospital Center, Mulhouse, France.
Cedric BruelIntensive Care Unit, Saint-Joseph Hospital Center, Paris, France.
Ahmed-Saïd LaggouneIntensive Care Unit, Regional Hospital Center, Guéret, France.
Delphine BregeaudIntensive Care Unit, Regional Hospital Center, Châteauroux, France.
Bertrand SouweineMedical Intensive Care Unit, Gabriel-Montpied University Hospital, Clermont-Ferrand, France.
Jean ReignierMédecine Intensive Réanimation, University Hospital, Nantes, France.
Jean-Baptiste LascarrouMédecine Intensive Réanimation, University Hospital, Nantes, France. jeanbaptiste.lascarrou@chu-nantes.fr.ORCID http://orcid.org/0000-0003-3706-078X
Centre Hospitalier Universitaire de Nantes · FRUniversité Clermont Auvergne · FRCentre Hospitalier Annecy Genevois · FRCentre Hospitalier d'Angoulême · FRCentre Hospitalier de Bretagne Sud · FRCentre Hospitalier de La Rochelle · FRCentre Hospitalier de Mulhouse · FRCentre Hospitalier de Saint-Brieuc · FRCentre Hospitalier de Saint-Malo · FRCentre Hospitalier de Versailles · FRCentre Hospitalier Public du Cotentin · FRCentre Hospitalier Sud Francilien · FRCentre Hospitalier Universitaire Amiens-Picardie · FRCentre hospitalier universitaire d'Orléans · FRCentre Hospitalier Victor Dupouy · FRCentre Jean Perrin · FRCentre Médical de La Teppe · FRCentre National de la Recherche Scientifique · FRHôpital Paris Saint-Joseph · FRHôpitaux Universitaires de Strasbourg · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNonintubated chest trauma patients with fractured ribs admitted to the intensive care unit (ICU) are at risk for complications and may require invasive ventilation at some point. Effective pain control is essential. We assessed whether epidural analgesia (EA) in patients with fractured ribs who were not intubated at ICU admission decreased the need for invasive mechanical ventilation (IMV). We also looked for risk factors for IMV. STUDY DESIGN AND

methodsThis retrospective, observational, multicenter study conducted in 40 ICUs in France included consecutive patients with three or more fractured ribs who were not intubated at admission between July 2013 and July 2015.

resultsOf the 974 study patients, 788 were included in the analysis of intubation predictors. EA was used in 130 (16.5%) patients, and 65 (8.2%) patients required IMV. Factors independently associated with IMV were chronic respiratory disease (P = 0.008), worse SAPS II (P < 0.0001), flail chest (P = 0.02), worse Injury Severity Score (P = 0.0003), higher respiratory rate at admission (P = 0.02), alcohol withdrawal syndrome (P < 0.001), and noninvasive ventilation (P = 0.04). EA was not associated with decreases in IMV requirements, median numerical rating scale pain score, or intravenous morphine requirements from day 1 to day 7.

conclusionsEA was not associated with a lower risk of IMV in chest trauma patients with at least 3 fractured ribs, moderate pain, and no intubation on admission. Further studies are needed to clarify the optimal pain control strategy in chest trauma patients admitted to the ICU, notably those with severe pain or high opioid requirements.

Indexed as

Chest traumaEpidural analgesia

Identifiers

PMID32852675
PMCPMC7450151
OpenAlexW3080162918

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.