Evidence map›Paper›PMID 32852612›Full record

ReviewCurrent hypertension reports2020

The Story of the Silent Killer : A History of Hypertension: Its Discovery, Diagnosis, Treatment, and Debates.

Jonathan P Kalehoff, Suzanne Oparil

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current hypertension reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 71 citations in OpenAlex.

  1. Life satisfaction and blood pressure: A coordinated analysis of 16 cohorts.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Semi-Synthetic HACS medicinal chemistry letters · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Hypertension Exacerbates Endothelial Dysfunction in Patients With Atrial Fibrillation.Journal of clinical hypertension (Greenwich, Conn.) · 2025
    Article
  10. Observational
  11. Article
  12. Review
  13. Article
  14. Article
  15. No Association BetweenDiabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jonathan P KalehoffTinsley Harrison Internal Medicine Residency Program, Division of Internal Medicine, Department of Medicine, The University of Alabama at Birmingham (UAB), Birmingham, AL, USA. jpkalehoff@uabmc.edu.
Suzanne OparilVascular Biology and Hypertension Program, Division of Cardiovascular Disease, Department of Medicine, School of Medicine,, The University of Alabama at Birmingham (UAB), 1720 2nd Avenue South, Birmingham, AL, 35294-0007, USA.
University of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertension is the leading risk factor for death and disability-adjusted life-years lost globally. Despite this tremendous impact on health, blood pressure measurement and treatment are relatively new to medical practice, with widespread measurement beginning just over 100 years ago. How, in such a short time, did blood pressure become such an integral measurement in medical practice that it is now considered one of the vital signs? Key revelations through Stephen Hales and his horse experiment, Riva-Rocci's modern blood pressure cuff, Korotkoff sounds, and President Roosevelt's death set the stage for discovery. Landmark trials such as the VA Cooperative studies of the 1960s through the recent Systolic Blood Pressure Intervention Trial and Prevention with Mediterranean Diet trials provide the foundation for modern clinical practice. An understanding of the history of hypertension can directly affect current clinical practice and offers unique insights into how the medical community has approached the management of one of the deadliest medical conditions in history.

Indexed as

Diet, MediterraneanHypertensionAnimalsBlood PressureBlood Pressure DeterminationHorsesHumansRisk FactorsAntihypertensive medication developmentBlood pressure goalsHypertension historyHypertension trialsKorotkoffOscillometrySphygmomanometer

Identifiers

PMID32852612
OpenAlexW3080403139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.