Evidence map›Paper›PMID 32852611›Full record

Trial reportInternational journal of colorectal disease2020

Impact of naturopathy, yoga, and dietary interventions as adjuvant chemotherapy in the management of stage II and III adenocarcinoma of the colon.

Kalpana Raghunath, Ch Sumathi, Senthil J Rajappa, M V T Krishna Mohan, Uday Kumar, Ummar Shaik, Mahendran Botlagunta

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in International journal of colorectal disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Immunomodulatory Effects in Healthy Individuals Following a 4-Week Taoist Qigong Intervention: A Comparative Study.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kalpana RaghunathDepartment of Academics, Basavatarakam Indo-American Cancer Hospital and Research Centre, Hyderabad, Telangana, India. kalpanaraghunath@induscancer.com.
Ch SumathiDepartment of Naturopathy and Yoga - Addlife, Basavatarakam Indo-American Cancer Hospital and Research Centre, Hyderabad, Telangana, India.
Senthil J RajappaDepartment of Medical Oncology, Basavatarakam Indo-American Cancer Hospital and Research Centre, Hyderabad, Telangana, India.
M V T Krishna MohanDepartment of Medical Oncology, Basavatarakam Indo-American Cancer Hospital and Research Centre, Hyderabad, Telangana, India.
Uday KumarDepartment of Naturopathy and Yoga - Addlife, Basavatarakam Indo-American Cancer Hospital and Research Centre, Hyderabad, Telangana, India.
Ummar ShaikIndian Institute of Information Technology and Management Kerala, Affiliated to Cochin University, Cochin, India.
Mahendran BotlaguntaDepartment of Indo American Cancer Research Foundation, Basavatarakam Indo-American Cancer Hospital and Research Centre, Hyderabad, Telangana, India. dr_bmnchowdary@induscancer.com.
Cancer Hospital and Research Institute · INIndian Institute of Information Technology and Management, Kerala · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNaturopathy, Yoga and Dietary interventions are known to improve the quality of life in cancer patients. We aim to evaluate the effect of naturopathy interventions along with adjuvant chemotherapy in patients who underwent surgery for Adenocarcinoma of the Colon.

methodsA total of 116 adult patients were randomised in to one of the two groups; the experimental group received naturopathy, Yoga and Dietary interventions and the control group received psycho-social counselling in addition to standard chemotherapy. Haematological, biochemical and psychological evaluations were performed at set intervals during a total period of eighteen months starting from the first cycle of adjuvant chemotherapy.

resultsResults showed that the overall hemoglobin (p < 0.0001) and carcinoembryonic antigen (CEA) (p = 0.0038) levels were statistically significant in patients on the experimental arm. The rest of the laboratory parameters, viz. total leukocyte count, platelet counts, and serum creatinine levels, for overall data was not statistically significant in both the groups. Psychological attributes such as anxiety, depression, symptom severity, and Functional Living Index: Cancer (FLIC) were found to be statistically significant (p < 0.0001) in the experimental subjects as compared with those in the control. On the whole, men benefited more than women from the study interventions.

conclusionsWe conclude that Yoga and Naturopathy interventions in addition to chemotherapy show improvement in overall functional life index along with improvement in haemoglobin in patients with stages II and III Adenocarcinoma of Colon.

Indexed as

AdenocarcinomaChemotherapy, AdjuvantColonic NeoplasmsNaturopathyYogaAdultFemaleHumansMaleQuality of LifeAdenocarcinoma of the colonDietary interventionsHematological parametersNaturopathyPsychological parametersYoga

Identifiers

PMID32852611
OpenAlexW3080755959

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.