SynthesisEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2020
Cancer and mortality risks of patients with scoliosis from radiation exposure: a systematic review and meta-analysis.
Synthesis in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 4 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- Long-term cancer risk in historic cohorts of patients with adolescent idiopathic scoliosis: a systematic review.Spine deformity · 2026Pooled it
- Pooled it
- Is there a skeletal age index that can predict accurate curve progression in adolescent idiopathic scoliosis? A systematic review.Pediatric radiology · 2024Pooled it
- Pooled it
- Evaluation of the effect of Rigo-Chêneau type brace on adolescent idiopathic scoliosis using computer-aided modeling and 3D surface analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- School-Based Scoliosis Screening Among Children and Adolescents - Wusu City, Xinjiang Uygur Autonomous Region, China, January 2026.China CDC weekly · 2026Article
- Kyphosis, lordosis and height velocity. What is the effect of rate of growth on the development of the sagittal parameters of the spine in normal children?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Radiation-free Assessment of Scoliosis: A Reliability and Validity Study for Ultrasound Angles.Global spine journal · 2026Article
- Radiation-free Cobb angle estimation in adolescent scoliosis using surface topography and a linear regression model.Spine deformity · 2026Article
- Advanced machine learning model for Cobb angle progression in adolescent idiopathic scoliosis with surface topography: a multicenter, prospective, observational study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Clinical relevance among optical, ultrasonic, and radiographic imaging in scoliosis assessment.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- 3D topographic acquisitions to predict spinal curvature in adolescent idiopathic scoliosis : a prospective validation study.Bone & joint open · 2026Article
- Automated CT dataset generation as a novel concept for verification of backshape-to-spine approach and Cobb Angle Estimation.PloS one · 2026Article
- Reference ranges and dimensional structure of upper body posture parameters in adults: a cross-sectional study.Frontiers in rehabilitation sciences · 2026Article
- Smartphone Monitoring of Guided Growth.Journal of the Pediatric Orthopaedic Society of North America · 2025Article
- Which slot scanning device is best for low-dose radiographs in pediatric scoliosis? A pilot study.Spine deformity · 2025Article
- Validity and reliability of 3D automatic ultrasound imaging for measuring coronal and sagittal angles in idiopathic scoliosis.Scientific reports · 2025Article
- Quantification of Thoracic Volume and Spinal Length of Pediatric Scoliosis Patients on Chest MRI Using a 3D U-Net Segmentation.Healthcare (Basel, Switzerland) · 2025Article
- A single-centre early experience of the Pulse™ navigation system for posterior spinal fusion in adolescent idiopathic scoliosis (AIS).Spine deformity · 2025Article
- Comparison of two ultrasound methods from ScolioscanEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
purposeThe study aimed for unraveling the long-term health impact of cumulative radiation exposure from full-spine radiographs on children/adolescents with scoliosis.
methodsAll cohort, case-control or cross-sectional studies about radiation exposure to scoliosis patients with follow-up period as 20 years or more were included. Meta-analyses were performed for outcomes reported in two or more studies.
resultsA total of 9 eligible studies involving 35,641 participants between 1912 and 1990 fulfilled the inclusion criteria, including 18,873 patients with scoliosis and 16,768 controls as regional matched general population. The average number of full-spine radiographs was 23.13 (range: 0-618) according to 14,512 patients between 1912 and 1990 in five studies. The estimated mean cumulated radiation dose of breast was 11.35 cGy. In comparison with controls, pooled incidence rates of cancer, breast cancer and cancer mortality of patients with scoliosis were statistically significant higher [rate of cancer, odds risk (OR) = 1.46, p < 0.00001; breast cancer, OR = 1.20, p = 0.02; cancer mortality, OR = 1.50, p < 0.00001]. No statistically significant differences were found in terms of reproductive events for scoliosis patients, pulmonary function and physical activity for adolescent idiopathic scoliosis patients.
conclusionsBased on 35,641 participants with over 20 years' observations from 1912 to 1990, repeated radiographs and pertaining cumulative radiation dose resulted in elevated rates of cancer, breast cancer and cancer mortality for children/adolescents with scoliosis in comparison with matched general population. It is recommended that low-radiation or radiation-free and efficient methods should be used to monitor the evolution of children/adolescents with scoliosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.