Evidence map›Paper›PMID 32852576›Full record

ArticlePediatric nephrology (Berlin, Germany)2021

COVID-19 associated with onset nephrotic syndrome in a pediatric patient: coincidence or related conditions?

Amado Alvarado, Gabriela Franceschi, Evelin Resplandor, Jeannethe Sumba, Nelson Orta

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Review
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  9. Kidney implications of SARS-CoV2 infection in children.Pediatric nephrology (Berlin, Germany) · 2022
    Review
  10. Renal manifestations of COVID 19 in children.Journal of family medicine and primary care · 2022
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Amado AlvaradoGeneral Hospital, Ecuatorian Institute of Social Security, IESS, Quito, Ecuador.
Gabriela FranceschiGeneral Hospital, Ecuatorian Institute of Social Security, IESS, Quito, Ecuador.
Evelin ResplandorGeneral Hospital, Ecuatorian Institute of Social Security, IESS, Quito, Ecuador.
Jeannethe SumbaGeneral Hospital, Ecuatorian Institute of Social Security, IESS, Quito, Ecuador.
Nelson OrtaUniversity of Carabobo, Valencia, Venezuela. nelson.orta@gmail.com.ORCID http://orcid.org/0000-0003-3725-498X
Instituto Ecuatoriano de Enfermedades Digestivas · ECUniversity of Carabobo · VE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOVID-19 is less frequent in children than in adults and affects the former less severely; despite the fact that respiratory symptoms are the most frequent, in some cases unusual manifestations can be seen. CASE-DIAGNOSIS: We present a 15-year-old boy who tested positive for SARS-COV-2 infection and onset of nephrotic syndrome, without antecedent of kidney disease and who had normal urine tests shortly before being affected by COVID-19.

conclusionsThe patient described in this report, who was admitted due to nephrotic syndrome and respiratory syndrome, tested positive for COVID-19. He, based on the data review by the researchers, is the first reported case of COVID-19 with simultaneous onset of complete picture of nephrotic syndrome. The presence of both diagnoses could be a coincidence or an unusual form of presentation of COVID-19.

Indexed as

AdolescentCOVID-19HumansMaleNephrotic SyndromePandemicsSARS-CoV-2AdolescentCovid-19Nephrotic syndromeProteinuriaSARS-COV-2

Identifiers

PMID32852576
PMCPMC7450156
OpenAlexW3081317339

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.