Evidence map›Paper›PMID 32852283›Full record

ArticleAging2020

Cortical aging - new insights with multiparametric quantitative MRI.

Alexander Seiler, Sophie Schöngrundner, Benjamin Stock, Ulrike Nöth, Elke Hattingen, Helmuth Steinmetz, Johannes C Klein, Simon Baudrexel, Marlies Wagner, Ralf Deichmann and 1 more

Open access · greenAbstract readComparative Study
In one paragraph

Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Normative trajectories of RImaging neuroscience (Cambridge, Mass.) · 2025
    Article
  6. Article
  7. Article
  8. Cortical microstructural involvement in cerebral small vessel disease.Cerebral circulation - cognition and behavior · 2024
    Article
  9. Article
  10. Article
  11. MRI of focal cortical dysplasia.Neuroradiology · 2022
    Review
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Alexander SeilerDepartment of Neurology, Goethe University, Frankfurt am Main, Germany.
Sophie SchöngrundnerDepartment of Neurology, Goethe University, Frankfurt am Main, Germany.
Benjamin StockDepartment of Neurology, Goethe University, Frankfurt am Main, Germany.
Ulrike NöthBrain Imaging Center, Goethe University, Frankfurt am Main, Germany.
Elke HattingenDepartment of Neuroradiology, Goethe University, Frankfurt am Main, Germany.
Helmuth SteinmetzDepartment of Neurology, Goethe University, Frankfurt am Main, Germany.
Johannes C KleinNuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
Simon BaudrexelDepartment of Neurology, Goethe University, Frankfurt am Main, Germany.
Marlies WagnerDepartment of Neuroradiology, Goethe University, Frankfurt am Main, Germany.
Ralf DeichmannBrain Imaging Center, Goethe University, Frankfurt am Main, Germany.
René-Maxime GracienDepartment of Neurology, Goethe University, Frankfurt am Main, Germany.
Goethe University Frankfurt · DEUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the microstructural changes related to physiological aging of the cerebral cortex is pivotal to differentiate healthy aging from neurodegenerative processes. The aim of this study was to investigate the age-related global changes of cortical microstructure and regional patterns using multiparametric quantitative MRI (qMRI) in healthy subjects with a wide age range. 40 healthy participants (age range: 2

Indexed as

Magnetic Resonance ImagingAdultAgedCerebral CortexCross-Sectional StudiesFemaleHealthy AgingHumansIronMaleMiddle AgedPredictive Value of TestsYoung AdultIroncortical agingiron depositionquantitative MRIsurface-based analysistissue microstructure

Identifiers

PMID32852283
PMCPMC7485732
OpenAlexW3081035319

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.