Evidence map›Paper›PMID 32851876›Full record

Trial reportThe American journal of drug and alcohol abuse2020

Variants of opioid genes and response to treatment of opioid use disorder with buprenorphine-naloxone versus extended-release naltrexone in Caucasians.

Matthew Randesi, John Rotrosen, Edward V Nunes, Joshua D Lee, Patricia Novo, Orna Levran, Jurg Ott, Martina Pavlicova, Jennifer Scodes, Mary Jeanne Kreek

Open access · bronzeAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The American journal of drug and alcohol abuse, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Matthew RandesiLaboratory of the Biology of Addictive Diseases, the Rockefeller University , New York, NY, USA.ORCID 0000-0003-3093-5141
John RotrosenDepartment of Psychiatry, NYU Grossman School of Medicine , New York, NY, USA.ORCID 0000-0002-0283-5576
Edward V NunesDepartment of Psychiatry, New York State Psychiatric Institute, Columbia University Medical Center , New York, NY, USA.ORCID 0000-0002-2055-3425
Joshua D LeeDepartment of Population Health, NYU Grossman School of Medicine , New York, NY, USA.ORCID 0000-0002-5907-0391
Patricia NovoDepartment of Psychiatry, NYU Grossman School of Medicine , New York, NY, USA.
Orna LevranLaboratory of the Biology of Addictive Diseases, the Rockefeller University , New York, NY, USA.ORCID 0000-0002-5136-4184
Jurg OttLaboratory of Statistical Genetics, the Rockefeller University , New York, NY, USA.ORCID 0000-0002-6188-1388
Martina PavlicovaDepartment of Biostatistics, Columbia University Mailman School of Public Health , New York, NY, USA.ORCID 0000-0003-4400-4102
Jennifer ScodesDivision of Mental Health Data Science, New York State Psychiatric Institute , New York, NY, USA.ORCID 0000-0002-5006-7436
Mary Jeanne KreekLaboratory of the Biology of Addictive Diseases, the Rockefeller University , New York, NY, USA.ORCID 0000-0001-8562-9091
Rockefeller University · USNew York University · USColumbia University · USColumbia University Irving Medical Center · USNew York State Office of Mental Health · US

Funding

Project-003UG1DA013035 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Aimee N Campbell, Jennifer McNeely · 2015 to 2026
$130.3M
Treatment Study Using Depot Naltrexone (3/6) NY/Bellevue Protocol Treatment SiteR01DA024555 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LEE, JOSHUA D · 2008 to 2014
$2.0M
Treatment Studies Using Depot Naltrexone (4/6) Columbia Protocol Treatment SiteR01DA024554 · NIDA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI NUNES, EDWARD V. · 2008 to 2014
$1.8M
Drug Abuse Treatment Development and Research MentoringK24DA022412 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI NUNES, EDWARD V. · 2007 to 2016
$1.7M
NIDA NIH HHS K24 DA022412NIDA NIH HHS R01 DA024554NIDA NIH HHS R01 DA024555NIDA NIH HHS UG1 DA013035
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Administration, SublingualAdultBuprenorphine, Naloxone Drug CombinationDelayed-Action PreparationsFemaleHumansInjections, IntramuscularMaleMiddle AgedNaltrexoneNarcotic AntagonistsOpioid-Related DisordersReceptors, OpioidWhite PeopleBuprenorphine, Naloxone Drug CombinationDelayed-Action PreparationsNaltrexoneNarcotic AntagonistsReceptors, OpioidBUP-NXopioid gene variantsresponse to treatmentxr-NTX

Identifiers

PMID32851876
PMCPMC8376218
OpenAlexW3080114847

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.