Evidence map›Paper›PMID 32851543›Full record

ReviewJournal of gastrointestinal cancer2020

Tumor Diameter for Hepatocellular Carcinoma: Why Should Size Matter?

Sertac Usta, Cuneyt Kayaalp

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of gastrointestinal cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  3. Competing risk analysis of surgical resectionTranslational cancer research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sertac UstaDepartment of Surgery, Liver Transplantation Institute, Inonu University, 44315, Malatya, Turkey. sertacusta44@gmail.com.ORCID https://orcid.org/0000-0003-0446-7073
Cuneyt KayaalpDepartment of Surgery, Liver Transplantation Institute, Inonu University, 44315, Malatya, Turkey.ORCID https://orcid.org/0000-0003-4657-2998

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere are two main goals in hepatocellular carcinoma management, the first is long term survival and the second is the low recurrence rate after the treatment. Therefore, a lot of selection criteria defined for each treatment method and tumor size is one of the most important parameter in almost all of them.

methodsIn this review, importance of diamater in hepatocellular carcinoma is reviewed.

resultsMany reports showed a significant association between increase in maximum tumor diameter and microvascular invasion. Patients with larger tumors are more likely to have poorly differentiated tumors. Increased regional and distant metastasis of tumors were observed in the larger size hepatocellular carcinoma. Liver transplantation represents the best treatment option for patients with decompensated liver cirrhosis and hepatocellular carcinoma.

conclusionsCombined with biological, inflammatory, radiological, pathological and genetic markers that predict the biological behavior of the tumor, today, tumor size is one of the best aggressiveness markers until new markers are found. So, tumor size is matter.

Indexed as

Patient SelectionTumor BurdenAblation TechniquesCarcinoma, HepatocellularChemoembolization, TherapeuticDisease-Free SurvivalHumansLiverLiver CirrhosisLiver NeoplasmsLiver TransplantationMolecular Targeted TherapyNeoplasm InvasivenessNeoplasm Recurrence, LocalRisk AssessmentSurvival RateHepatocellular carcinomaTumor diameterTumor size

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.